Putative antidiabetic herbal food ingredients: Nutra/functional properties, bioavailability and effect on metabolic pathways

Publication date: Available online 22 January 2020Source: Trends in Food Science &TechnologyAuthor(s): Isra Ismail IID, Satish Kumar, Swati Shukla, Vikas Kumar, Rakesh SharmaAbstractThe utilization of herbal medicines for the management of diseases has provided admirable results. Plant extracts are rich in like polyphenols, alkaloids, glycosides, flavonoids, and terpenoids having specific health benefits. Diabetes mellitus (DM) is a non-communicable disease with a worldwide occurrence, characterized by persistent hyperglycemic conditions. Several oral hypoglycemic drugs viz. sulfonylureas, biguanides, α-glucosidase inhibitors, and non-sulfonylureas secretagogues are common medical recommendations for controlling diabetes. Consumption of oral hypoglycemic drugs demonstrate prominent side effects and to date, no permanent effective remedy for the complete recovery of DM is available. Until effective medication procedures are established; complementary and alternative medicines must be utilized to reduce the disease incidence. WHO has put herbal medicines on their priority list to treat various illnesses as they have lesser side effects, ease of access, affordability and low cost. Their administration can impart comparative functionality like medicine, if extracted in pure forms. Herbal antidiabetic formulations like dia-care, diabecure, syndrex, quath, churna, arth, vati etc are commercially available in the market. Identification of particular bioactive compound, min...
Source: Trends in Food Science and Technology - Category: Food Science Source Type: research

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Source: Drug Development and Industrial Pharmacy - Category: Drugs & Pharmacology Tags: Drug Dev Ind Pharm Source Type: research
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Source: European Journal of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research
AbstractPurposeTo explore the effect of nighttime sleep duration and midday napping in early pregnancy on gestational diabetes mellitus (GDM) among Chinese women.MethodsInformation on midday napping and nighttime sleep duration was assessed by a questionnaire. Diagnostic information of GDM was derived from the routine oral glucose tolerance test (OGTT) during the second trimester of pregnancy.ResultsA total of 500 pregnant women, including 196 patients with GDM and 304 controls, were included in the present study. In the case group, 47% of women took a midday nap>  1 h/day, and the proportion was 22% in the ...
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
MicroRNAs (miRNAs) are a class of small non-coding RNA molecules that regulate gene expression. There is increasing evidence that some miRNAs are involved in the pathology of diabetes mellitus (DM) and its com...
Source: Journal of Orthopaedic Surgery and Research - Category: Orthopaedics Authors: Tags: Research article Source Type: research
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Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Original Research: Obstetrics Source Type: research
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Source: Acta Diabetologica - Category: Endocrinology Source Type: research
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Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Biological Sciences Source Type: research
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