HIV coinfections with tuberculosis among HIV-1 infected individuals in old cross river state, Nigeria.
This study evaluated the HIV/TB co-infection rate among HIV-1 infected individuals in old Cross River State, Nigeria. A total of 417 HIV-infected individuals participated in this study, 241 (57.8%) from Calabar, Cross River State, Nigeria and 176 (42.2%) from Uyo, Akwa-Ibom State, Nigeria. The age range of the 417 HIV-1 positive individuals who participated in the study was 4-72 years with an average age of 39.1 years. Plasma samples were analyzed for HIV and TB using fourth-generation Enzyme-Linked immunosorbent Assay. The CD4 count was enumerated using the Partec CyFlow® Counter. Plasma viral loads (PVL) were determined using the Abbott Real-Time HIV-1 assay. Results showed that 230 (55.2%) of the participants were in the 31-45 years age range. The majority (67.4%) of the HIV-1 infected individuals were females and 32.6% were males. An overall prevalence of HIV/TB coinfection in Old Cross River State, Nigeria was 1.4%, with Akwa Ibom State (0.6%) and Cross River State (1.2%). A higher prevalence of HIV/TB coinfection was observed among females (1.8%) than in males (0.7%). Higher prevalences of HIV/TB coinfections was observed in patients above 45 years of age (2.2%), married (2.3%), tertiary education (1.8%) followed by those with secondary education (1.4%), traders and civil servants (3.1%), patients with CD4 counts 200-349 and ≥500 cells/μl (1.9%), and those with viral load
Publication date: Available online 31 March 2020Source: Microbial PathogenesisAuthor(s): Jôsimar D. Moreira, Henrique Rodrigues Silva, Vicente de P.C.P. de Toledo, Tânia M.P.D. Guimarães
Publication date: Available online 31 March 2020Source: Preventive Veterinary MedicineAuthor(s): Tiny Motlatso Hlokwe, Marcia Mogano Ratanna
This report provides an overview of the latest tuberculosis (TB) epidemiological situation in Europe.
CONCLUSION: Evaluation of immune status based on PD-L1 pleural concentration and Th2 to Th1 ratio might predict the risk of MDR-TB occurrence. PMID: 32224537 [PubMed - in process]
[Daily Maverick] Covid-19 has been declared a pandemic by the World Health Organisation. In South Africa, multiple cases and several deaths have been confirmed. While the fight to contain the pandemic continues, a major area of concern is the additional vulnerability of those with TB and HIV to Covid-19, particularly those who are not on treatment.