Detection of Hepatitis C virus and the risk of transmission among pregnant and nursing mothers from rural and urban communities in Kogi State, Nigeria.

Detection of Hepatitis C virus and the risk of transmission among pregnant and nursing mothers from rural and urban communities in Kogi State, Nigeria. J Immunoassay Immunochem. 2020 Jan 20;:1-14 Authors: Ifeorah IM, Bakarey AS, Akubo AO, Onyemelukwe FN Abstract Hepatitis C virus (HCV) is associated with liver complicated diseases resulting in end-stage hepatocellular carcinoma. Although vertical transmission from mother to child serves as one of the routes of HCV acquisition in children, yet HCV infection in pregnant women and children is still underappreciated in sub-Saharan Africa. Therefore, this study investigated the burden of HCV, associated risk factors, and viremia among antenatal and postnatal clinic attendees in the rural and urban communities of Kogi State, Nigeria. Atotal of 176 blood samples were collected from 78 (44.32%) consenting breastfeeding (nursing) mothers and 98 (55.8%) pregnant mothers (age ranged 18-47 years) (SD = +12.1; Median = 26.3) and tested for anti-HCV by ELISA technique. All anti-HCV-positive samples were retested by Taq one-step RT-PCR technique for viral RNA (viremia) detection. The bio-socio-demographic variables of the participants were correlated with the test results, using an IBM SPSS version 21 and MEOP 2010. Ameasure of goodness was considered significant at P
Source: Journal of Immunoassay and Immunochemistry - Category: Biochemistry Tags: J Immunoassay Immunochem Source Type: research

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Abstract Hepatitis C virus (HCV) infection is a silent killer that leads to rapid progression of liver cirrhosis and hepatocellular carcinoma (HCC). High prevalence of HCV infection has been reported in Taiwan, especially in high-risk populations including people who inject drugs (PWID) and patients requiring dialysis. Besides, certain populations merit special considerations due to suboptimal outcome, potential drug-drug interaction, or possible side effect. Therefore, in the second part of this 2-part consensus, the Taiwan Association for the Study of the Liver (TASL) proposes the treatment recommendations for t...
Source: J Formos Med Assoc - Category: General Medicine Authors: Tags: J Formos Med Assoc Source Type: research
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Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
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Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
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Source: AIDS Reviews - Category: Infectious Diseases Authors: Tags: AIDS Rev Source Type: research
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Source: Infezioni in Medicina - Category: Infectious Diseases Tags: Infez Med Source Type: research
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Source: Internal Medicine Journal - Category: Internal Medicine Authors: Tags: Clinical Perspectives Source Type: research
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Source: - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
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Source: Gastroenterology Clinics of North America - Category: Gastroenterology Authors: Source Type: research
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