The GRADE approach to appraising the evidence or how to increase the credibility of your research

One of the early meta-analyses on the timing of laparoscopic cholecystectomy after an episode of acute cholecystitis, published in 2006, included 4 studies with a cumulative number of 504 participants randomized to early or delayed laparoscopic cholecystectomy.1 The authors found similar perioperative outcomes and a shorter hospital stay in patients undergoing early cholecystectomy. Since this publication, a number of cohort studies, randomized controlled trials (RCTs) and meta-analyses have found similar results and, additionally, have demonstrated a lower risk of wound infection following early cholecystectomy.
Source: American Journal of Surgery - Category: Surgery Authors: Source Type: research