Safety and Efficacy of Bipolar vs Monopolar Transurethral Resection of Bladder Tumor-A Randomized Controlled Trial

Condition:   Obturator Jerk in TURBT Intervention:   Device: TURBT Sponsor:   Tribhuvan University, Nepal Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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ConclusionsThe state of the pharmacoepigenetic literature on antipsychotic use is still in its early stages and uniform reporting of methylation site information is needed. Future work should concentrate on using prospective sampling with appropriate control groups and begin to replicate many of the novel associations that have been reported.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Category: Drugs & Pharmacology Authors: Tags: REVIEW OF THERAPEUTICS Source Type: research
Conclusions: Certain modifiable risk factors play an inescapable role in increasing the level of burden among caregivers of older patients with serious mental illnesses.Clinical Implications: Improving the quality of life and psychological well-being of family caregivers should be considered an integral part of treatment for serious mental illness in older adult patients. PMID: 32058858 [PubMed - as supplied by publisher]
Source: Clinical Gerontologist - Category: Geriatrics Tags: Clin Gerontol Source Type: research
Publication date: April 2020Source: Materials Science and Engineering: R: Reports, Volume 140Author(s): Shumeng Wang, Hongyang Zhang, Baohua Zhang, Zhiyuan Xie, Wai-Yeung WongAbstractSolution-processed organic light-emitting diodes (s-OLEDs) have received a great deal of interest owing to the huge market application potentials as large-size, flexible, high-quality self-luminous display panels and lighting sources. It is anticipated that those electronic products can be easily manufactured by modern wet-processing techniques, e.g. ink-jet printing and ‘roll-to-roll’ coating methods. However, issues related to po...
Source: Materials Science and Engineering: R: Reports - Category: Materials Science Source Type: research
Publication date: 25 June 2020Source: Journal of Alloys and Compounds, Volume 827Author(s): Dai-Wen Tao, Zi-Jin Jiang, Jian-Biao Chen, Xiao-Gang Wang, Yan Li, Cheng-Wei WangAbstractHere, the Cu/Al/FTO layered nanostructure was designed and manufactured for investigating the roles of the interface transition layers in its resistive switching (RS) behaviors. The presence of the interface transition layers was confirmed by X-ray photoelectron spectroscopy (XPS) depth profile scans, indeed there is a very thin Al2O3 interface transition layer (interface 1, denoted as I1) produced by the natural oxidation within the Cu/Al inter...
Source: Journal of Alloys and Compounds - Category: Chemistry Source Type: research
Authors: Steardo L, Manchia M, Carpiniello B, Pisanu C, Steardo L, Squassina A Abstract Introduction: Early detection and intervention in bipolar disorder (BD) might reduce illness severity, slow its progression, and, in specific cases, even ward off the full-blown disorder. Therefore, identifying at-risk individuals and targeting them promptly before the illness onset is of the utmost importance. In the last decades, there has been a significant effort aimed at identifying genetic and molecular factors able to modulate risk and pharmacological outcomes.Areas covered: We performed a narrative review of articles aim...
Source: Expert Review of Molecular Diagnostics - Category: Laboratory Medicine Tags: Expert Rev Mol Diagn Source Type: research
The objective of this study is to track and compare acute manic symptoms for sex differences during inpatient hospitalization.MethodsAll patients with bipolar mania admitted to a large university hospital between January and October 2017 were invited to participate in this longitudinal naturalistic follow ‐up study. Manic (YMRS), depressive (MADRS), and psychotic (PAS) symptoms were tracked daily from admission to discharge.ResultsThe total YMRS scores decreased significantly overtime (p 
Source: Brain and Behavior - Category: Neurology Authors: Tags: ORIGINAL RESEARCH Source Type: research
This study aimed to investigate epigenetic modulations of the hepatic PPARγ pathway in olanzapine-induced lipid dysfunctions. Olanzapine led to significant increases of body weight gain, white adipose tissue, fasting triglyceride, and fat accumulation in the liver. A significant upregulation of PPARγ was observed in olanzapine-treated rats. ChIP-deep sequencing showed the increase of H3K4me2 binding on the whole gene loci of key regulators of adipogenesis and lipogenesis, the Pparg, Srebp-1, Cebps families (Cebpa, Cebpb and Cebpd), the Signal transducer and activator of transcription 5 families (Stat5a and Stat...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
ConclusionsThe state of the pharmacoepigenetic literature on antipsychotic use is still in its early stages and uniform reporting of methylation site information is needed. Future work should concentrate on using prospective sampling with appropriate control groups and begin to replicate many of the novel associations that have been reported.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Category: Drugs & Pharmacology Authors: Tags: REVIEW OF THERAPEUTICS Source Type: research
Publication date: 15 June 2020Source: Journal of Alloys and Compounds, Volume 826Author(s): Tsung-Ming Tsai, Chun-Chu Lin, Wen-Chung Chen, Cheng-Hsien Wu, Chih-Cheng Yang, Yung-Fang Tan, Pei-Yu Wu, Hui-Chun Huang, Yong-Ci Zhang, Li-Chuan Sun, Sheng-Yao ChouAbstractIn this paper, we investigate two different resistive switching mechanisms in sputtered nickel oxide thin film which result from using the forming compliances of 15 μA and 15 mA. X-ray photoelectron spectroscopy material analysis results verify the nickel and oxygen chemical shifts, while energy-dispersive X-ray spectroscopy results confirm oxygen co...
Source: Journal of Alloys and Compounds - Category: Chemistry Source Type: research
AbstractThere is increasing evidence from genetic, biochemical, pharmacological, neuroimaging and post-mortem studies that immunological dysregulation plays a crucial role in the pathogenesis of psychoses. The involvement of microglia in schizophrenia and bipolar disorder (BD) has remained controversial, however, since results from various post-mortem studies are still inconclusive. Here, we analyzed the estimated density of microglia of age-matched individuals with schizophrenia (n = 17), BD (n = 13), and non-psychiatric control subjects (n = 17) in the anterior midcingulate corte...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Neuroscience Source Type: research
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