PTP1B Implication in the Vascular Dysfunction Associated With Obstructive Sleep Apnea
Conditions: Sleep Apnea; Inflammation; Atherosclerosis Intervention: Other: myeloid PTP1B expression analysis Sponsor: University Hospital, Angers Not yet recruiting
ConclusionsCompared with the general population, the prevalence of elevated CVP and OSA is significant in this cohort of patients. Age, diabetes, and right lower extremity chronic venous insufficiency symptoms seem to be predictors of elevated CVP. Larger, population-based prevalence studies are needed to confirm these findings.
This study was a prospective, single cohort of consecutive adult patients undergoing MMA surgery for OSA at a single institution. The primary outcome measure was the development of nasal obstruction using the Nasal Obstruction Symptom Evaluation scale. Secondary outcomes included the rate of reintubation, submandibular duct function, development of neck infection, the need for subsequent surgical correction of nasal obstruction, and changes in the Apnea-Hypopnea Index.ResultsTwenty consecutive patients (85% male, mean age 47 years) were included in the study. Nasal Obstruction Symptom Evaluation scores improved in 88% of p...
Publication date: Available online 20 February 2020Source: The Annals of Thoracic SurgeryAuthor(s): Bhargavi Gali, Amy E. Glasgow, Kevin L. Greason, Rebecca L. Johnson, Robert C. Albright, Elizabeth B. HabermannAbstractBackgroundObstructive sleep apnea (OSA) is associated with increased risk of postoperative complications in non-cardiac surgery, with limited literature on cardiac surgical patients. We compared perioperative outcomes of patients with OSA to those without OSA undergoing cardiac surgery.MethodsThis was a retrospective single center cohort study of adult patients who underwent cardiac surgery from January 2010...
ConclusionIn this study, we observed significant positive correlations between plasma vimentin level and OSA severity, weight, AHI, and mean oxygen desaturation. Vimentin may have utility as a biomarker in the follow-up and treatment of OSA.
Authors: Dzięciołowska-Baran E, Gawlikowska-Sroka A, Szczurowski J Abstract Polysomnography, a gold standard for the diagnosis of sleep-disordered breathing, is a complex investigation requiring access to the sleep laboratory. Thus, sleep-disordered breathing could be underdiagnosed. The aim of this paper was to investigate the feasibility and effectiveness of self-performed investigation of obstructive sleep apnea (OSA) in the home setting, using a portable device, and to assess the comfort and simplicity of the procedure from the patient's perspective. The study included 68 middle-aged patients (21 women and 47...
Publication date: Available online 20 February 2020Source: Journal of Evidence Based Dental PracticeAuthor(s): Kimberly Fluger, Alan Zhou, Thikriat Al-Jewair
ConclusionsAnterior osteotomy just to the midline of inferior border and horizontal osteotomy to the mandibular foramen are associated with split patterns that result in optimal rigid fixation and passive bony overlap for OSA patients undergoing MMA.Clinical relevanceOptimal surgical technique has the most significant influence in allowing rapid return to function after MMA in patients with OSA.
The purpose of this study was to determine if submental intubation during maxillomandibular advancement (MMA) reduces the development of nasal obstruction in patients with obstructive sleep apnea (OSA).
PMID: 32083949 [PubMed - as supplied by publisher]
Patients with previous acute coronary syndrome treated with CPAP for obstructive sleep apnea showed no significant reduction in subsequent cardiovascular events, in a randomized trial.Medscape Medical News