Unique optical coherence tomographic features in age-related macular degeneration

Age-related macular degeneration (AMD) is a leading cause of blindness worldwide characterized by presence of drusen, leading to retinal pigment epithelium (RPE) and outer retinal changes in advanced stages. Approximately 10% of eyes with AMD develop neovascular complications and present with subretinal or sub-RPE exudation, hemorrhage, or both. Recent advances in imaging techniques, especially optical coherence tomography (OCT), help in early identification of disease and guide various treatment decisions; however, not all signs are suggestive of ongoing exudation or neovascular activity.
Source: Survey of Ophthalmology - Category: Opthalmology Authors: Tags: Major review Source Type: research