Safety and efficacy of sildenafil citrate to reduce operative birth for intrapartum fetal compromise at term: A Phase 2 Randomized Controlled Trial

Sildenafil citrate is a vasodilator used in erectile dysfunction and pulmonary hypertension. We tested whether it reduces emergency operative births for fetal compromise and improves fetal or utero-placental perfusion in labor in a Phase II double blind randomized controlled trial.

Source: American Journal of Obstetrics and Gynecology - January 20, 2020 Category: OBGYN Authors: Jessica TURNER MRCOG, Liam DUNN, William Tarnow-Mordi, Christopher Flatley, Vicki Flenady, Sailesh KUMAR Tags: Report of Major Impact Source Type: research