High serum substance P levels and mortality after malignant middle cerebral artery infarction

Publication date: Available online 20 January 2020Source: Journal of Critical CareAuthor(s): Leonardo Lorente, María M. Martín, Antonia Pérez-Cejas, Agustín F. González-Rivero, Mónica Argueso, Luis Ramos, Jordi Solé-Violán, Juan J. Cáceres, Alejandro Jiménez, Victor García-MarínAbstractPurposePreviously our team found higher serum substance P concentrations at day 1 of a malignant middle cerebral artery infarction (MMCAI) in non-surviving than in surviving patients. Thus, the objective of this study was to determine whether serum substance P levels during the first week of MMCAI could predict mortality.MethodsWe included patients with MMCAI defined as computed tomography findings of acute infarction in at least of 50% of the territory and Glasgow Coma Scale≤8. We determined serum concentrations of substance P on days 1, 4 and 8 of MMCAI. Thirty-day mortality was the study end-point.ResultsSerum substance P concentrations at days 1 (p 
Source: Journal of Critical Care - Category: Gastroenterology Source Type: research

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Conclusion: These updated French guidelines will contribute to increase the level of urological care for the diagnosis and treatment for NMIBC and MIBC. PMID: 32093463 [PubMed - in process]
Source: Progres en Urologie - Category: Urology & Nephrology Tags: Prog Urol Source Type: research
Authors: Hosokawa T, Suzuki S, Tanami Y, Sato Y, Ko Y, Nomura K, Oguma E, Yamada Y Abstract In contrast to computed tomography, ultrasound can be performed without radiation exposure, repeatedly performed by the patients' bedside. Hence, in this case series, we describe the evaluation of complications including hematoma, superficialsurgical site infection, mediastinitis, and pseudoaneurysm associated mediastinitis using ultrasound in pediatric patients after cardiovascular surgery. To our knowledge, no previous reports have evaluated such complications using ultrasound. Ultrasound may be useful for the early diagno...
Source: Medical Ultrasonography - Category: Radiology Tags: Med Ultrason Source Type: research
Authors: Maconi G, Sousa M Abstract Gastrointestinal ultrasound (GIUS) has been increasingly used for the management of gastrointestinal disorders due to its potentialities as a cheap, widely available and safe examination with comparable accuracy to other techniques such as Computed Tomography or Magnetic Resonance Imaging. However, some limitations have been stated to justify its underuse such as its dependency on the operator, small field of view and penetration and need of expertise. However, most of these limitations are inherent to any technique. The main problems with GIUS are lack of standardized definition...
Source: Medical Ultrasonography - Category: Radiology Tags: Med Ultrason Source Type: research
Authors: Roman A, Palego F, Achimas-Cadariu P, Vlad C, Andries A, Tomuleasa CI, Gata VA, Pintican R, Rada MP, Feier D Abstract AimsThe present study aims to investigate the pain, anxiety and other factors that are associated with percutaneous computed tomography (CT)- and ultrasound (US)-guided biopsies of tumors.Material and MethodsThe study prospectively included 60 consecutive patients, of which 24 underwent CT-guided biopsies and 36 US-guided biopsies. The location of targeted tumors was within the thorax, abdomen, pelvis, and limbs. A questionnaire containing numerical rate scales (0-10) regarding procedural a...
Source: Medical Ultrasonography - Category: Radiology Tags: Med Ultrason Source Type: research
CONCLUSIONS: EUS guided fine needle aspiration/biopsy of focal liver lesions is safe, provides a very high diagnostic accuracy and should not be considered only as a rescue method after failure of percutaneous guided biopsies. PMID: 32096783 [PubMed - as supplied by publisher]
Source: Medical Ultrasonography - Category: Radiology Tags: Med Ultrason Source Type: research
DISCUSSION: For a diagnosis of primary breast cancer of the vulva, a thorough metastatic workup should be performed, with attention directed toward detecting a breast primary disease by results of the history, physical examination, and radiologic examination of the breasts mainly to help confirm that the vulvar lesion is the primary site as opposed to metastasis from a breast primary cancer and also for staging. Management of this rare entity is challenging because of a lack of specific guidelines, and treatment, therefore, is similar to that of breast cancer.Treatment should consist of an individualized combination of sur...
Source: The Permanente journal - Category: General Medicine Tags: Perm J Source Type: research
DISCUSSION: The pathogenesis of frontal sinus cholesteatoma varies based on its cause (congenital vs acquired). Clinical diagnosis remains challenging but is aided by nasal endoscopy, computed tomography, and magnetic resonance imaging. Historically, FSC has been managed by total extirpation through open approaches, which can entail substantial morbidity. With sophisticated endoscopic sinus instrumentation and image guidance, FSC can be successfully treated via an endoscopic approach. Serial débridements and washouts in an outpatient setting may adequately manage the residual disease in the postoperative period. ...
Source: The Permanente journal - Category: General Medicine Tags: Perm J Source Type: research
This study was performed in Zhongshan Hospital, Fudan University, China. 803 patients with hypertension were consecutively recruited from 2012 to 2015. All participants underwent routine biochemical measurements, including plasma renin activity (PRA) and plasma aldosterone concentration (PAC). In all patients with a PAC higher than 10 ng/dl, a saline perfusion test was conducted, and a CT scan or adrenal venous sampling was also performed if needed. Receiver operating characteristic (ROC) analysis was conducted in all eGFR 
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Publication date: Available online 25 February 2020Source: Academic RadiologyAuthor(s): Gamal Eldine Niazi, Mohammad Abd Alkhalik Basha, Walid Feisal Ali Elsharkawi, Mohamed M.A. Zaitoun
Source: Academic Radiology - Category: Radiology Source Type: research
AbstractOn 14 June 2017 at 00:54  h, the worst residential fire since the conclusion of the Second World War broke out in Flat 16, 4th floor of the 24-storey residential Grenfell Tower Block of flats, North Kensington, West London, UK. Seventy-one adults and children died, including one stillbirth. All victims of the Grenfell Towe r disaster who died at the scene underwent post-mortem computed tomography (PMCT) imaging using a mortuary-sited mobile computed tomography scanner. For the first time, to the authors’ knowledge, the disaster victim identification (DVI) radiology reporting was undertaken remote to the ...
Source: International Journal of Legal Medicine - Category: Medical Law Source Type: research
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