First-trimester placental function in levothyroxine-using pregnant women: a case-control study

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Source: Gynecological Endocrinology - Category: Endocrinology Authors: Source Type: research

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This study aimed to evaluate fertility in female survivors of childhood DTC by assessing various reproductive characteristics combined with anti-Müllerian hormone (AMH) levels (a marker of ovarian reserve). Methods. Female survivors of childhood DTC, diagnosed at ≤18 years of age between 1970 and 2013 were included. Survivors were excluded when follow-up time was less than 5 years or if they developed other malignancies before or after diagnosis of DTC. Survivors filled out a questionnaire regarding reproductive characteristics (e.g. age at menarche and menopause, pregnancies, pregnancy outcomes, need for assisted ...
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Sarah Novotny, Nicole Lee-Plenty, Kedra Wallace, Wondwosen Kassahun-Yimer, Aswathi Jayaram, James A. Bofill, James N. MartinAbstractObjectiveTo determine the prevalence of acute kidney injury (AKI), placental abruption and postpartum hemorrhage in patients with preeclampsia or HELLP syndrome.Study designA retrospective study of patients with preeclampsia or HELLP syndrome treated at the University of Mississippi Medical Center from January 2000 through December 2010.Main outcome measuresRelationships among the obstetric complications of place...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Laura A Magee, Joel Singer, Terry Lee, Richard J McManus, Sarah Lay-Flurrie, Evelyne Rey, Lucy C Chappell, Jenny Myers, Alexander G Logan, Peter von DadelszenAbstractObjectiveTo examine the relationship between pregnancy outcomes and BP level and variability.DesignSecondary analysis of CHIPS trial data (Control of Hypertension In Pregnancy Study, NCT01192412).SettingInternational.Population or sampleWomen with chronic or gestational hypertension.MethodsBP measurement was standardised in outpatient clinics. Adjusted (including for allocated gr...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Cecilia Villalain, Ignacio Herraiz, Borja Cantero, Soledad Quezada, Ana Lopez, Elisa Simón, Alberto GalindoAbstractObjectivesThe optimal timing for delivery in non-severe late-preterm (34 + 0–36 + 6 weeks) preeclampsia (PE) is uncertain. It is attempted to reach term pregnancy safely but current clinical and analytical parameters fail to determine which cases will develop severe features that require preterm delivery. We aim to establish if angiogenic biomarkers may identify cases that would benefit from ...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Mohamed Rezk
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Ellie Proussaloglou, Ariel Mueller, Ruby Minhas, Sarosh RanaAbstractObjectivesHypertensive disorders of pregnancy are a leading cause of maternal morbidity and mortality. Although acute severe hypertension carries with it a poor prognosis, treatment is often delayed and not universal.Study designA total of 654 patients were assessed for the impact of hypertensive disorders of pregnancies on maternal and fetal morbidity and divided into three groups: normotensive (Group I, N = 306), non-severe hypertension (Group II, N = 24...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
ConclusionAspirin resistance was found in a considerable part of the participants. Considerable variation between participants, within participants over time and between the different devices was found. Prevalence of aspirin resistance during pregnancy differs from after pregnancy. More research on aspirin resistance and clinical obstetric outcome is needed.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
ConclusionsCardiac effects after severe late-onset PE were small and transient. This indicates that left ventricular hypertrophy after severe late-onset PE may be a secondary physiologic response to increased peripheral resistance in PE. Vascular mechanisms rather than persistent cardiac hypertrophy postpartum may be the culprit for increased long-term cardiovascular risk after PE.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
ConclusionsPlacental bed vacuum suction provides more spiral arteries and higher AA rate, suggesting underestimation of AA in conventional pathology samples of basal plate DB biopsies and DP. The association of AA with PE-related clinical parameters varies according to tissue collection method. Longitudinal studies could elucidate whether AA also identifies women with future premature cardiovascular risk.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Erkan Kalafat, Can Benlioglu, Basky Thilaganathan, Asma KhalilAbstractRecent evidence suggests that home blood pressure monitoring (HBPM) is an effective way of managing women with hypertensive disorders of pregnancy (HDP) without increasing adverse outcomes. The aim of this systematic review and meta-analysis was to investigate the safety and efficacy of HBPM during pregnancy.Medline, EMBASE and the Cochrane library databases were searched electronically in November 2018. Studies were included from which data could be extracted on the pregna...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
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