A Novel Approach to Sensory Re-innervation to the Nipple Areolar Complex after Mastectomy with Implant-Based Reconstruction: Anatomic and Technical Considerations

Breast cancer is the most commonly diagnosed invasive cancer in women worldwide. The physical and psychological consequences of breast cancer can be somewhat mitigated with reconstruction, making it an integral part of the treatment approach in women requiring mastectomy.1 With improvements in surgical management, increasing amounts of the native breast skin can be spared with oncologic safety. This skin sparing approach has improved aesthetic outcomes, but it does not affect the loss of sensation in the breast, one of the most commonly reported deficiencies after mastectomy.
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - Category: Cosmetic Surgery Authors: Tags: Correspondence and Communications Source Type: research

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AbstractFungating breast cancer (FBC) is a rare entity in developed nations. But this occurrence is not uncommon in our country. The aim of this study was to review clinico-pathologic profile and outcomes of FBC in a developing country. This retrospective study consisted of patients with FBC managed at our institute (Jan 2005 –Dec 2015). Clinico-pathologic profile, management details, and outcomes were analyzed. The Kaplan-Meier method was used to determine overall survival (OS). Log-rank test was performed to compare survival in various subgroups. Seventy-nine patients were detected to have FBC constituting 3.3% of ...
Source: Indian Journal of Surgical Oncology - Category: Cancer & Oncology Source Type: research
: Robotic nipple sparing mastectomy (R-NSM) and immediate gel implant breast reconstruction (IGBR) in the management of breast cancer had comparable clinical outcome with conventional nipple sparing mastectomy (C-NSM) and IGBR. R-NSM was associated with favorable patients ’ satisfaction of aesthetic outcome, however, at the price of longer operation time and more medical expanse if compared with C-NSM.
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - Category: Cosmetic Surgery Authors: Tags: Original Article Source Type: research
A 64-year old female with a history of a pulmonary embolism on rivaroxaban, breast cancer (mastectomy in 2013), hypertension, and diabetes presented for fatigue for one month. She had intermittent hemoptysis for six months. She was brought to the emergency department complaining of fatigue. Blood pressure was elevated to 165/75 mmHg. On exam, she appeared lethargic with pale conjunctiva and leg edema. She did not have a skin rash. Laboratory studies were significant for creatinine of 15.3 mg/dL, blood urine nitrogen 140 mg/dL, potassium 6.5 mEq/L.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Clinical Communication to the Editor Source Type: research
AbstractPurpose of ReviewWe review the management for unaffectedBRCA1/2 mutation carriers and the local management of early-stage breast cancer.Recent FindingsFor unaffectedBRCA1/2 mutation carriers, surveillance includes annual magnetic resonance imaging (MRI) and mammogram (MG). Novel imaging modalities, including abbreviated protocol MRI, ultrafast/accelerated MRI, and contrast-enhanced digital mammography are being investigated. Risk-reducing mastectomy (RRM) should be considered, and nipple-areolar sparing mastectomy (NSM) is now an option. Additionally, risk-reducing salpingo-oophorectomy (RRSO) is strongly recommend...
Source: Current Breast Cancer Reports - Category: Cancer & Oncology Source Type: research
Abstract BACKGROUND AND PURPOSE: There is limited retrospective evidence addressing the utility of post-mastectomy radiotherapy (PMRT) in patients with T3N0 breast cancer. We performed a retrospective analysis of the National Cancer Database (NCDB) comparing overall survival (OS) in T3N0 patients treated with mastectomy alone (MTX) or with PMRT. MATERIALS AND METHODS: We performed a matched-cohort analysis of NCDB breast cancer patients with pT3N0 disease who did not receive NAC, or cT3N0 patients who received NAC treated between 2006 and 2014. Patients were matched for all available baseline characteristics ...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
Background and Objectives: Whether post-mastectomy radiotherapy (PMRT) could improve prognosis for T1-2 breast cancer patients with one to three lymph node metastases remains controversial. The present study aimed to determine the significance of PMRT in patients with T1-2N1M0 breast cancer.Methods: Data of 45,646 patients from the Surveillance, Epidemiology, and End Results (SEER) database were analyzed; 12,585 matched patients were divided into a PMRT group and non-radiotherapy group (no-PMRT), respectively, using the propensity score matching method. Univariate and multivariate analyses were performed to determine the p...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
ConclusionsXDFI-CT is useful for exploring the microanatomy of the human nipple and might be used for non-invasive nipple diagnosis in the future.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
Conditions:   Anatomic Stage II Breast Cancer AJCC v8;   Anatomic Stage IIA Breast Cancer AJCC v8;   Anatomic Stage IIB Breast Cancer AJCC v8;   Anatomic Stage IIIA Breast Cancer AJCC v8;   Invasive Breast Carcinoma;   Prognostic Stage II Breast Cancer AJCC v8;   Prognost ic Stage IIA Breast Cancer AJCC v8;   Prognostic Stage IIB Breast Cancer AJCC v8;   Prognost...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionOur results showed that the clinical outcomes and complication rates of periareolar incisions for breast reconstruction were equivalent to those of inframammary fold incisions, suggesting that the periareolar incision technique for breast reconstructive surgery may safely improve cosmetic outcomes if done with adequate care.
Source: Surgery Today - Category: Surgery Source Type: research
AbstractSince the late 1990s, the use of contralateral prophylactic mastectomy (CPM) to treat unilateral breast cancer has been on the rise. Over the past two decades, dozens of studies have been conducted in order to understand this trend, which has puzzled and frustrated physicians who find it at odds with efforts to curb the surgical overtreatment of breast cancer, as well as with evidence-based medicine, which has established that the procedure has little oncologic benefit for most patients. Based on the work of Annemarie Mol and John Law, this paper argues that these efforts to understand increased CPM use are limited...
Source: Journal of Medical Humanities - Category: Medical Ethics Source Type: research
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