Therapeutic potential of algal natural products against metabolic syndrome: A review of recent developments

Publication date: Available online 20 January 2020Source: Trends in Food Science &TechnologyAuthor(s): I.P. Shanura Fernando, BoMi Ryu, Ginnae Ahn, In-Kyu Yeo, You-Jin JeonAbstractBackgroundMetabolic syndrome (MS) defines a group of severe comorbidities, including insulin resistance, abnormal fat accumulation, and high blood pressure that lead to obesity, diabetes, and heart diseases. MS has received a growing concern due to its rising prevalence in many countries. The consumption of high-calorie food, sedentary lifestyle habits, genetic factors, and stress conditions aggravate risk factors for developing metabolic syndrome. Investigations targeting the development of marine algae-based functional food products and drug candidates for attenuating MS have presently received increased attention.Scope and approachThis review delivers an overview of recent (past ten years) advancements in discovering marine algal natural products with therapeutic potential against metabolic syndrome. Pathophysiology of obesity, diabetes mellitus, hypertension, and the action mechanisms of algal natural products are taken into the discussion.Key findings and conclusions:Marine algae, a popular ingredient in East Asian cuisine, is proven to be a source of nutritional and biofunctional natural products with promising ability to remedy MS. These include bioactive polyphenols, sulfated polysaccharides, terpenoids, alkaloids, polyunsaturated fatty acids, and peptides with vast structural diversity....
Source: Trends in Food Science and Technology - Category: Food Science Source Type: research

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Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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Source: American Journal of Clinical Dermatology - Category: Dermatology Source Type: research
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