Localized Scleroderma in the Pediatric Population

Localized scleroderma is an uncommon condition that affects the skin and underlying tissues. Although the pathogenesis is not well understood, lesions of localized scleroderma develop from an initial inflammatory reaction that results in collagen deposition, fibrosis, and atrophy. Healthcare providers need to be alert for skin discolorations or atypical ecchymosis appearances that do not resolve. Prompt diagnosis and treatment, particularly in pediatric patients, are necessary to reduce the risk of growth disturbance, extremity length differences, permanent damage to the skin, accessory structures, joints, and facial atrophy (Careta & Romiti, 2015). Delayed treatment is associated with worse outcomes (Martini et al., 2018). Consensus-based recommendations provide effective treatment options; however, more studies are required in the pediatric population as, to date, there is only one randomized controlled trial in this population (Constantin et al., 2018).
Source: JDNA: Journal of the Dermatology Nurses Association - Category: Dermatology Tags: FEATURE ARTICLES Source Type: research