Risk of Breast Implant Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) in a Cohort of 3546 Women Prospectively Followed Long Term After Reconstruction with Textured Breast Implants
: The risk of BIA-ALCL for patients with textured breast implants has been estimated between 1/2832 and 1/30,000 women. Existing studies estimating the numbers exposed and at risk, may have under reported cases, and/or lacked comprehensive follow-up. Our objective is to determine the risk of BIA-ALCL in a defined cohort of patients reconstructed with macro-textured breast implants and consistently followed long-term.
We present a case report of an adult woman with AKL-positive ALCL, diagnosed by endobronchial ultrasound-guided transbronchial needle aspirate (EBUS-TBNA).A 59-year-old women with no history of breast implants, was admitted for a four-month low back pain. Initially, the patient was treated for a spondyloarthropathy, but due to persistence of the symptoms, a lumbosacral MRI was performed, showing changes in morphology and signal intensity in the vertebral body of L3, along with edema and a paravertebral collection that affected the left psoas muscle, suggesting granulomatous spondylodiscitis. Chest CT-scan showed mild left ...
No abstract available
During the last two decades, the number of breast implants used in aesthetic, oncologic and risk reducing surgery has exponentially increased. Since the identification of the first case of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) more than twenty years ago , several cases on this very rare disease have been reported, demonstrating a clear association with breast implants. As a result, the World Health Organization (WHO) recognized BIA-ALCL as a disease associated with excellent outcomes in the 2017 classification of haemato-lymphoid neoplasms .
Exclusive: solicitors call for UK ban of textured variety associated with lymphomaAt least 61 women in the UK have been diagnosed with a potentially fatal cancer linked to breast implants, but the type they received continues to be used, with no plans by the regulator to follow France and Australia in banning them.Lawyers for more than 40 of the women, who are bringing legal action against the manufacturers as well as the clinics and doctors who carried out the surgery, say thetextured implants linked toanaplastic large cell lymphoma (ALCL) should be withdrawn from the market. Smooth implants are available instead, which h...
Condition: Anaplastic Large Cell Lymphoma Associated With Breast Implants (BIA-ALCL) Intervention: Other: BIA-ALCL Sponsor: The Lymphoma Academic Research Organisation Recruiting
AbstractThe choice between anatomical and round implants is an important decision in breast augmentation surgery; however, both have their place and the decision between them that should be made on a patient-by-patient basis, taking into account the patient ’s desires, anatomy, and surgical history. In some individuals, there are clear indications for using either anatomical or round devices, and there is good evidence that aesthetic outcomes are better with anatomical implants in some instances. When both types are an option, anatomical devices may offer increased flexibility and, despite a longer learning curve nee...
Canadian women with textured breast implants now banned by Health Canada over links to a rare form of lymphoma have to decide whether the cost of having them removed outweighs the risk of leaving them in.
ConclusionLymphoma is not a common disease in patients with prostheses, and more data are needed to identify risk factors and make proper diagnoses.Level of Evidence IIIThis journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authorswww.springer.com/00266.