Discovering hidden information in biosignals from patients by artificial intelligence.

Discovering hidden information in biosignals from patients by artificial intelligence. Korean J Anesthesiol. 2020 Jan 16;: Authors: Yoon D, Jang JH, Choi BJ, Kim TY, Han CH Abstract Biosignals like electrocardiogram or photoplethysmogram have been widely used for monitoring and determining status of patients. However, it has been recently discovered that more information than that we have used traditionally were included in the biosignals after artificial intelligence (AI) was applied. Most meaningful advancement of current AI was in deep learning. The deep learning-based models show the best performance in most area in current due to the distinguished characteristic that it is able to extract important features from raw data. For that, deep learning extracts features in data by itself without feature engineering by human, if amount of data is enough for that. These AI-enabled feature give us opportunities to have a chance to see novel information which was hidden for many decades. It will be able to be used as digital biomarker for detecting or for predicting clinical outcome or event without further or more invasive evaluation. However, because the characteristics of deep learning is black box model, it is difficult to understand to use if users have the traditional view on the biosignals. For properly use of the novel information which is being discovered by AI and for adopting that in real clinical practice, clinicians need to basic knowledge on the A...
Source: Korean Journal of Anesthesiology - Category: Anesthesiology Tags: Korean J Anesthesiol Source Type: research

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Publication date: Available online 18 February 2020Source: Best Practice &Research Clinical AnaesthesiologyAuthor(s): Andrea De Gasperi, Gregorio Spagnolin, Martina Ornaghi, Laura Petrò, Gianni BiancofioreAbstractNew and extended indications, older age, higher cardiovascular risk, and the long-standing cirrhosis - associated complications mandate specific skills for an appropriate preoperative assessment of the LT candidate. The incidence of cardiac diseases (dysrhythmias, cardiomyopathies, coronary artery disease, valvular heart disease) are increasing among LT recipients: however, no consensus exists among cli...
Source: Best Practice and Research Clinical Anaesthesiology - Category: Anesthesiology Source Type: research
Conclusions In this trial, there does not appear to be a significant difference in electrocardiographic changes in patients with Brugada syndrome when propofolversus etomidate were administered for induction of anesthesia. This study did not investigate electrocardiographic changes related to propofol used as an infusion for maintenance of anesthesia, so future studies would be warranted before conclusions about safety of propofol infusions in patients with Brugada syndrome can be determined.Editor ’s PerspectiveWhat We Already Know about This TopicBrugada syndrome is an inherited cardiac ion channel disorder that pl...
Source: Anesthesiology - Category: Anesthesiology Source Type: research
We report a case of a 35 weeks pregnant woman who presented in emergency with sudden-onset palpitations and mild shortness of breath with no personal/family history of cardiac diseases. Diagnoses: Patient's pulse was irregularly irregular with an average rate of 179 beats per minute. The obstetric examination was normal. Diagnosis: High-sensitive cardiac troponin T (hs-cTnT) was elevated. The 12 lead electrocardiogram (ECG) confirmed AF. The obstetric ultrasound, electronic fetal heart rate (EFHR) trace, and maternal echocardiography were normal. Interventions: The patient was admitted under joint cardiology and o...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Publication date: Available online 30 January 2020Source: Chemico-Biological InteractionsAuthor(s): Faheem Sultan, Rajdeep Kaur, Arshad Hussain Mir, Ishfaq Maqbool, Milindmitra Lonare, Digvijay Singh, Satyavan Rampal, Javeed Ahmad DarAbstractCardiovascular disorders constitute the principal cause of deaths worldwide and will continue as the major disease-burden by the year 2060. A significant proportion of heart failures occur because of use and misuse of drugs and most of the investigational agents fail to achieve any clinical relevance. Here, we investigated rosuvastatin and retinoic acid for their “pharmacological...
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
We present a case of a 36-year-old woman (Gravida 0, Para 0) with abnormal uterine bleeding-leiomyoma and resultant anemia, undergoing hysteroscopic resection of a large submucous myoma. During surgery, the patient was found to have a critically elevated level of carboxyhemoglobin and accompanying electrocardiogram derangements. She was managed with prolonged intubation, 100% O2, and trending of her carboxyhemoglobin levels before extubation. This demonstrates the importance of being cognizant of the potentially toxic gaseous byproducts of bipolar resection and of including intravasation of these byproducts in one's consid...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Rosuvastatin and retinoic acid may act as 'pleiotropic agents' against β-adrenergic agonist-induced acute myocardial injury through modulation of multiple signalling pathways. Chem Biol Interact. 2020 Jan 30;:108970 Authors: Sultan F, Kaur R, Mir AH, Maqbool I, Lonare M, Singh D, Rampal S, Dar JA Abstract Cardiovascular disorders constitute the principal cause of deaths worldwide and will continue as the major disease-burden by the year 2060. A significant proportion of heart failures occur because of use and misuse of drugs and most of the investigational agents fail to achieve any clinical rele...
Source: Chemico-Biological Interactions - Category: Molecular Biology Authors: Tags: Chem Biol Interact Source Type: research
We report anesthetic management in a patient with Brugada syndrome, an inherited syndrome characterized by normal QT interval, typical ST-segment-elevation in the right precordial leads, and increased risk of sudden cardiac death in the absence of myocardial ischemia or structural heart disease. A 69-year-old man scheduled for glaucoma filtering surgery underwent local peribulbar anesthesia using 5 mL of lidocaine 20 mg/mL solution that was slowly injected into two different sites approximately 10 min prior to the surgical procedure. The surgery proceeded uneventful and data of patient's blood pressure, heart...
Source: European Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Eur J Ophthalmol Source Type: research
Abstract Atrial fibrillation is the most common cardiac arrhythmia in western society affecting more than 35 million individuals worldwide annually. It is a common postoperative complication and may also occur spontaneously during general and local anesthesia administration. Aging, diabetes mellitus, hypertension, and cardiovascular diseases including cardiomyopathies, congenital cardiac anomalies, heart failure, myocardial ischemia, pericarditis, previous cardiac surgery, vascular disease, and valvular heart disease are some correlated factors. Beyond age, increased incidence of atrial fibrillation has been corre...
Source: Annals of Cardiac Anaesthesia - Category: Anesthesiology Authors: Tags: Ann Card Anaesth Source Type: research
Abstract OBJECTIVE: Major lower limb amputation is the highest risk lower limb procedure in vascular surgery. Despite this, few high quality studies have examined factors contributing to mortality. The aim was to identify independent risk factors for peri-operative morbidity and mortality and develop reliable models for estimating risk. METHODS: All patients undergoing lower limb amputation above the ankle entered into the UK National Vascular Registry (January 2014-December 2016) were included. Missing data were handled using multiple imputation. Models were developed to evaluate independent risk factors for...
Source: PubMed: Eur J Vasc Endovasc ... - Category: Surgery Authors: Tags: Eur J Vasc Endovasc Surg Source Type: research
Authors: Lu Y, Di M, Li C, Chen M, Yuan K, Shangguan W Abstract Pulse oximetry and measurement of regional cerebral oxygen saturation (rcSO2) are used to monitor peripheral and cerebral oxygenation, respectively. However, the response of rcSO2 and pulse oxygen saturation (SpO2) to hypoxia in preschool children has not been previously assessed. A total of 36 preschool patients who had undergone a tonsillectomy [age, 4-6 years, American Society of Anesthesiologists grade I or II] were screened and prospectively enrolled in the present study. Hemodynamics, including rcSO2, SpO2, non-invasive blood pressure, heart rate...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
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