Neuroprotection by Sildenafil: Neuronal Networks Potentiation in Acute Experimental Stroke.

CONCLUSIONS: Sildenafil produces significant neuroprotective effects on injured neurons in acute stroke, and these are mediated by the cGMP-dependent Nogo-R pathway, NGF/TrkA, and BDNF/TrkB. PMID: 24034153 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24034153?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - August 30, 2013 Category: Neuroscience Authors: Chen XM, Wang NN, Zhang TY, Wang F, Wu CF, Yang JY Tags: CNS Neurosci Ther Source Type: research