A good night ’s sleep helps repair inflammation | Letter

This should become the number one priority in public health, writesDr Guru SinghExcellent article by Edward Bullmore in Journal (Inflammation is the new frontier in public health, 20 January). Unfortunately it does not fully explore the role of prevention. It is nowbeing proven that sleep plays a major role in repairing the body, and in particular the brain, especially from the ravages of inflammation. After all, why do we sleep?Inflammation is an essential part of our existence – it’s the way the body responds to an attack from without or within. Unfortunately this also causes damage in other areas, including the brain. Hence the value of a good night’s sleep.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Sleep Health Society & wellbeing Life and style Mindfulness Mental health Medical research Science Source Type: news

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Abstract Sleep-wake disturbances are both a risk factor and reported morbidity for intracerebral hemorrhage (ICH). ICH begins with a ruptured blood vessel and blood leakage into the parenchyma. In response to initial damage, pathophysiological processes ensue that both exacerbate and repair damage. Inflammation is a hallmark process of ICH, which includes microglia activation and increased cytokine signaling. Due to the dual role of cytokines as inflammatory signaling proteins and sleep regulatory substances (SRSs), we hypothesized that ICH would activate microglia, increase SRSs, and alter sleep-wake patterns fol...
Source: Experimental Neurology - Category: Neurology Authors: Tags: Exp Neurol Source Type: research
This study evaluates the relationship of PA to outcomes after open ventral hernia repair (OVHR).MethodsA prospective institutional database was queried for patients undergoing OVHR. Demographics, operative characteristics, and outcomes were evaluated by the reported PA and the administration of beta-lactam prophylaxis (BLP).ResultsAllergy histories were reviewed in 1178 patients. PA was reported in 21.6% of patients, with 55.5% reporting rash or hives, 15.0% airway compromise or anaphylaxis, and 29.5% no specific reaction. BLP was administered to 76.3% of patients, including 22.1% of PA patients and 89.9% of patients witho...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
Going through alcohol withdrawal can be an uncomfortable experience. Fortunately there are medical interventions that can ease the symptoms of detox as well as help individuals along their journey through recovery. Medically assisted treatment (MAT) is the use of medications in combination with counseling and behavioral therapies, which is effective in the treatment of substance abuse and can help some people to sustain recovery. Medically assisted treatment for alcohol can help people recovering from alcohol use disorder by blocking cravings, avoiding relapse, and helping to rewire the brain’s chemistry. Medication...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Alcohol Alcohol Rehab Information Alcoholism Detox Resources for Alcohol and Drugs/Opiates alcohol detox drug detox medical detox medicated-assisted detox Source Type: blogs
CONCLUSIONS: Buccinator re-repair (Bs + Re: IVVP) has been shown to be an effective and safe procedure in treating difficult postpalatoplasty velopharyngeal incompetence. It was also shown that it is still a physiological nonobstructive procedure with low morbidity. PMID: 31973560 [PubMed - as supplied by publisher]
Source: The Cleft Palate-Craniofacial Journal - Category: ENT & OMF Authors: Tags: Cleft Palate Craniofac J Source Type: research
(University of Arizona) Daily exposure to blue wavelength light each morning helps to re-entrain the circadian rhythm so that people get better, more regular sleep which was translated into improvements in cognitive function, reduced daytime sleepiness and actual brain repair.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
I just finished 14 days of daily blogging (15 if we include this post), publishing an article called Sculpting Your Character 7 minutes before midnight last night. That was fun piece to write. đŸ™‚ The commitment of this one-year daily blogging challenge is energizing and motivating. And my writing is becoming faster, easier, and more flowing. Previously I’d prefer to blog in the morning. I love the early morning hours and like to get up around 5am. But with the current Stature course launch happening (2 days left to go), my blogging time has shifted to later in the day sometimes, like starting at 9 or 10 pm or...
Source: Steve Pavlina's Personal Development Blog - Category: Psychiatry & Psychology Authors: Tags: Abundance Creating Reality Lifestyle Productivity Source Type: blogs
This study indicates alteration of molecular change s with sleep in old mice.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
toi E Abstract INTRODUCTION: We review the literature and highlight the important factors to consider when counselling patients with non-traumatic rotator cuff tears on which route to take. Factors include the clinical outcomes of surgical and non-surgical routes, tendon healing rates with surgery (radiological outcome) and natural history of the tears if treated non-operatively. METHODS: A PRISMA-compliant search was carried out, including the online databases PubMed and EMBASE from 1960 to the end of June 2018. FINDINGS: A total of 49 of the 743 (579 PubMed and 164 EMBASE) results yielded by the prelim...
Source: Annals of the Royal College of Surgeons of England - Category: Surgery Authors: Tags: Ann R Coll Surg Engl Source Type: research
Abstract Factors motivating patients to undergo rotator cuff repair (RCR) have not been thoroughly investigated. The purpose of this study was to investigate patient and surgeon decision-making factors for RCR, as well as the use of conservative treatment, and their relationship with shoulder function. A total of 144 adult patients undergoing arthroscopic RCR completed a 13-item questionnaire assessing the importance of surgical decision-making factors. Preoperative conservative treatments were also recorded. Surgeons also completed a similar 5-item questionnaire assessing surgeon decision-making factors preoperat...
Source: Orthopedics - Category: Orthopaedics Authors: Tags: Orthopedics Source Type: research
ConclusionJiao-tai-wan has the potential to attenuate systemic inflammation and cognitive impairment in partially sleep-deprived rats. The possible underlying mechanism is by preventing an inflammation trigger being transferred through the gut-brain-axis.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
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