Effects of yolkin on the immune response of mice and its plausible mechanism of action.

In conclusion, this is a first demonstration of immunotropic properties of yolkin in in vitro and in vivo tests. The results provide evidence for induction of maturation and stimulatory signals in immature T and B cells by the protein, suggesting its potential role in the development of an embryo's immune system.
PMID: 31954800 [PubMed - as supplied by publisher]

Source: Immunology Letters - January 15, 2020 Category: Allergy & Immunology Authors: Obmińska-Mrukowicz B, Szczypka M, Lis M, Pawlak A, Suszko-Pawłowska A, Sysak A, Zambrowicz A, Burster T, Kocięba M, Artym J, Zaczyńska E, Kochanowska I, Zimecki M Tags: Immunol Lett Source Type: research