Lymphatic Leakage after Surgery for Neuroblastoma: A Rare Complication?

Conclusion We show that LL in neuroblastoma is a common complication of tumor resection and occurring more often than anticipated. Since, in our study cohort, all cases of LL were self-limiting, we question the indication for invasive therapy besides supporting measures. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: European Journal of Pediatric Surgery - Category: Surgery Authors: Tags: Original Article Source Type: research

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In this study, polydimethylsiloxane-based microfluidic devices were designed, fabricated, and characterized to produce silk particles through self-association of silk when exposed to PVA. Three main variables resulted in differences in particle size and size distribution, or polydispersity index (PDI). Utilizing a co-flow microfluidic device decreased the PDI of the silk particles as compared to an emulsion-based method (0.13 versus 0.65, respectively). With a flow-focusing microfluidics device, lowering the silk flow rate from 0.80 to 0.06 mL/h resulted in a decrease in the median particle size from 6.8 to 3.0 μm a...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Series Type : Genome variation profiling by arrayOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Genome variation profiling by array Homo sapiens Source Type: research
Contributor : Annalisa PezzoloSeries Type : Genome variation profiling by arrayOrganism : Homo sapiensGenomic aberrations of neuroblastoma occurring in late childhood and adolescence are uncommon and still underestimated.Public DNA copy number profiles of 556 tumors (discovery set) and of 208 tumors obtained by array-CGH assay (validation set) were used to verify if 19p loss is significantly over-represented in children and adolescents. The 19p loss occurrence was separately tested within different age groups in the discovery and validation set and the resulting P values were combined and corrected by Bonferroni ’s m...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Genome variation profiling by array Homo sapiens Source Type: research
Contributor : Annalisa PezzoloSeries Type : Genome variation profiling by arrayOrganism : Homo sapiensGenomic aberrations of neuroblastoma occurring in late childhood and adolescence are uncommon and still underestimated.Public DNA copy number profiles of 556 tumors (discovery set) and of 208 tumors obtained by array-CGH assay (validation set) were used to verify if 19p loss is significantly over-represented in children and adolescents. The 19p loss occurrence was separately tested within different age groups in the discovery and validation set and the resulting P values were combined and corrected by Bonferroni ’s m...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Genome variation profiling by array Homo sapiens Source Type: research
Contributor : Annalisa PezzoloSeries Type : Genome variation profiling by arrayOrganism : Homo sapiensGenomic aberrations of neuroblastoma occurring in late childhood and adolescence are uncommon and still underestimated.Public DNA copy number profiles of 556 tumors (discovery set) and of 208 tumors obtained by array-CGH assay (validation set) were used to verify if 19p loss is significantly over-represented in children and adolescents. The 19p loss occurrence was separately tested within different age groups in the discovery and validation set and the resulting P values were combined and corrected by Bonferroni ’s m...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Genome variation profiling by array Homo sapiens Source Type: research
Contributor : Annalisa PezzoloSeries Type : Genome variation profiling by arrayOrganism : Homo sapiensGenomic aberrations of neuroblastoma occurring in late childhood and adolescence are uncommon and still underestimated.Public DNA copy number profiles of 556 tumors (discovery set) and of 208 tumors obtained by array-CGH assay (validation set) were used to verify if 19p loss is significantly over-represented in children and adolescents. The 19p loss occurrence was separately tested within different age groups in the discovery and validation set and the resulting P values were combined and corrected by Bonferroni ’s m...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Genome variation profiling by array Homo sapiens Source Type: research
Contributor : Annalisa PezzoloSeries Type : Genome variation profiling by arrayOrganism : Homo sapiensGenomic aberrations of neuroblastoma occurring in late childhood and adolescence are uncommon and still underestimated.Public DNA copy number profiles of 556 tumors (discovery set) and of 208 tumors obtained by array-CGH assay (validation set) were used to verify if 19p loss is significantly over-represented in children and adolescents. The 19p loss occurrence was separately tested within different age groups in the discovery and validation set and the resulting P values were combined and corrected by Bonferroni ’s m...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Genome variation profiling by array Homo sapiens Source Type: research
Publication date: Available online 13 February 2020Source: Pharmacological ResearchAuthor(s): Swadesh K. Das, Santanu Maji, Stephen L. Wechman, Praveen Bhoopathi, Anjan K. Pradhan, Sarmistha Talukdar, Devanand Sarkar, Joseph Landry, Chunqing Guo, Xiang-Yang Wang, Webster K. Cavenee, Luni Emdad, Paul B. FisherAbstractThe primary cause of cancer-related death from solid tumors is metastasis. While unraveling the mechanisms of this complicated process continues, our ability to effectively target and treat it to decrease patient morbidity and mortality remains disappointing. Early detection of metastatic lesions and approaches...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Authors: Yeşil E, Çelebi S, Sezgin Evim M, Özer A, Turan C, Timur D, Çakır SÇ, Bülbül B, Ener B, Güneş AM, Köksal N, Özkan H, Sevinir B, Düzcan Kilimci D, Hacımustafaoğlu M Abstract Micafungin is recommended especially in patients with liver and kidney failure and in the presence of other side effects due to antifungals apart from its known priority indications such as invasive candidiasis. The aim of this study was to evaluate the children who have received micafungin treatment. In the study, 125 children who were hospitalized in the pediatric wards and ...
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
This study delineates the role of MYCN in the cell death induced by combination treatment of rapamycin and MK-2206 in MYCN-amplified NB cells.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
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