Abnormal glucose tolerance and the 50-gram glucose challenge test in Cystic fibrosis

Cystic fibrosis related diabetes (CFRD), a common complication in cystic fibrosis, is associated with worse clinical outcomes [1 –4], and increases disease burden while adversely impacting quality of life [5]. Early diagnosis and treatment of CFRD may mitigate the associated decline in lung function, decreases in body mass index (BMI), and increased mortality [6–8]. Earlier glucose derangements during 75 g oral glucose c hallenge test (OGTT) such as impaired glucose tolerance (IGT; 2-hr OGTT glucose ≥7.8 mmol/L and

Source: Journal of Cystic Fibrosis - January 19, 2020 Category: Respiratory Medicine Authors: Saba Sheikh, A Russell Localio, Andrea Kelly, Ronald C Rubenstein Tags: Short Communication Source Type: research