Sarcopenia in Community-Dwelling Oldest Old is Associated with Disability and Poor Physical Function

Conclusion and implicationsWe found over a quartile of the community-dwelling oldest old in China had sarcopenia. Older age, lower BMI, and worse nutritional status were significantly associated with the presence of sarcopenia. Sarcopenia was independently associated with disability and poor physical function.
Source: The Journal of Nutrition, Health and Aging - Category: Nutrition Source Type: research

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AbstractThe SynGAP protein is a major regulator of synapse biology and neural circuit function. Genetic variants linked to epilepsy and intellectual disability disrupt synaptic function and neural excitability. SynGAP has been involved in multiple signaling pathways and can regulate small GTPases with very different functions. Yet, the molecular bases behind this pleiotropy are poorly understood. We hypothesize that different SynGAP isoforms will mediate different sets of functions and that deciphering their spatio ‐temporal expression and subcellular localization will accelerate understanding their multiple functions. U...
Source: Journal of Neurochemistry - Category: Neuroscience Authors: Tags: ORIGINAL ARTICLE Source Type: research
Paul Dodenhoff writes on disability hate crime and a possible sensitive and controversial issue amongst disability organisations and campaign groups
Source: Disabled World - Category: Disability Tags: Editorials Source Type: news
Advances in molecular profiling of tumor cells have increased potential of evolution of cancer cells and showcased need for early cancer diagnosis and personalized disease management
Source: Disabled World - Category: Disability Tags: Market Research Source Type: news
Whiplash injuries account for approximately 70% of all injuries leading to disability, induced by modern vehicle crashes. Females are at greater risk for sustaining whiplash injuries than males, which may be attributable to differences in the physiology of...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
Publication date: Available online 17 February 2020Source: The Egyptian RheumatologistAuthor(s): Rehab A. Sallam, Amany S. ElbahnasawyAbstractAim of the workTo assess health-related quality of life (HRQoL) and associated variables in Egyptian ankylosing spondylitis (AS) patients.Patients and methods50 male patients with AS and 50 age-matched controls were enrolled. Clinical and laboratory data were examined including history for peripheral arthritis. Visual analog scale (VAS), Bath AS disease activity index (BASDAI), AS disease activity score (ASDAS)-C-reactive protein (CRP) and ASDAS-erythrocyte sedimentation rate (ESR), ...
Source: The Egyptian Rheumatologist - Category: Rheumatology Source Type: research
What are the recommended vaccinations for older adults? This review offers practical guidance on appropriate vaccines and their timing, as well as vaccination in older populations with special needs.Journal of the American Geriatrics Society
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Internal Medicine Journal Article Source Type: news
Sep 16, 2020. . Sponsored by National Indigenous Women's Resource Center
Source: Rural events via the Rural Assistance Center - Category: Rural Health Source Type: events
Publication date: April 2020Source: Research in Developmental Disabilities, Volume 99Author(s): Katie Cebula, Hanna Kovshoff
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
Conclusions and implicationsGiven the heightened vulnerability to distress among parents of children with multiple developmental disabilities, psychological care should particularly target this population. Early identification and intervention strategies are also needed to detect children with multiple co-occurring developmental disabilities, which could potentially alleviate their emotional and behavioral problems and lessen the parenting burden.
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
Stroke is a major cause of death and disability across the world, with many reviews from the Cochrane Stroke Group providing evidence on the effects of treatments and rehabilitation interventions. In November 2019, the Group published their update of their review of selective serotonin reuptake inhibitors and we asked lead author, Gillian Mead from the University of Edinburgh in Scotland, to tell us more.
Source: Podcasts from The Cochrane Library - Category: General Medicine Authors: Source Type: podcasts
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