Ultrasound Versus Contrast-Enhanced Magnetic Resonance Imaging for Subclinical Synovitis and Tenosynovitis: A Diagnostic Performance Study

CONCLUSION: Ultrasound could be as sensitive and specific as contrast-enhanced MRI for the diagnosis of subclinical synovitis and tenosynovitis.
Source: Clinics - Category: General Medicine Source Type: research

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AbstractPurpose of ReviewThis is a comprehensive literature review of the available evidence and techniques of foot injections for chronic pain conditions. It briefly describes common foot chronic pain syndromes and then reviews available injection techniques for each of these syndromes, weighing the available evidence and comparing the available approaches.Recent FindingsFoot and ankle pain affects 20% of the population over 50 and significantly impairs mobility and ability to participate in activities of daily living (ADLs), as well as increases fall risk. It is commonly treated with costly surgery, at times with questio...
Source: Pain and Therapy - Category: Anesthesiology Source Type: research
(Natural News) Rheumatoid arthritis is an autoimmune disease that causes inflammation and pain by attacking the synovial tissues within the joints. This often affects the joints of the hands, wrists, feet, knees, elbows and ankles. The American College of Rheumatology estimates that rheumatoid arthritis affects about 1.3 million Americans, with 75 percent of these patients...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
ConclusionOur evidence suggests that iguratimod may be considered a potential alternative to methotrexate to treat rheumatoid arthritis.Key Points•The Asia Pacific League of Association for Rheumatology (APLAR) has recommended that iguratimod may be used a first-line drug for rheumatoid arthritis in specific cases.•Patients on iguratimod may have similar treatment response, functional ability, disease state, and adverse event profile at 24  weeks compared with those on methotrexate.•Iguratimod may be considered a better alternative to methotrexate in RA patients having high CRP and ESR values.•Futu...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
Conclusions: These data suggest biomarker analysis can reflect disease activity across disease domains in PsA. Certain domains would likely benefit from evaluation of additional biomarkers. PMID: 32067517 [PubMed - as supplied by publisher]
Source: Expert Review of Clinical Immunology - Category: Allergy & Immunology Tags: Expert Rev Clin Immunol Source Type: research
AbstractPain is a health issue affecting all populations, regardless of age, gender, economic status, race, or geography. Acute pain is the most common type of pain, with a complex aetiology. Inadequately managed acute pain adversely affects quality of life and imposes significant economic burden. The majority of the available pain-relieving drugs have monomodal mechanisms of analgesia, which necessitates combining drugs with non-redundant mechanisms of action in order to provide adequate pain relief and reduce the side effects from higher doses of individual drugs. In this regard, combining an oral opioid (such as codeine...
Source: Pain and Therapy - Category: Anesthesiology Source Type: research
ConclusionA review of the literature identified only few cases of closed avulsion of FDS tendons nonpathologically. Early diagnosis and intervention can prevent sequel of flexion contracture.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Scenario 1: Direct Billing A 70-year-old female patient with rheumatoid arthritis in multiple joints and positive rheumatoid factor returns to the practice for her fourth infusion of infliximab with the nurse practitioner (NP). She reports no fevers, cough, dyspnea or concurrent illness. She rates the severity of her joint pain at 6 on a 10-point... [Read More]
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Billing/Coding From the College Medicare nurse practitioner physician assistant Source Type: research
ConclusionsTofacitinib efficacy can be re-established after temporary withdrawal and reinitiation. The safety profile of patients who temporarily discontinued tofacitinib in the sub-study was consistent with previous tofacitinib LTE studies over 9  years.Clinical trial registration numberNCT00413699Key Points•In this sub-study of the long-term extension (LTE) study, ORAL Sequel, the efficacy of tofacitinib was re-established after temporary withdrawal (2  weeks) and reinitation of treatment in patients with RA.•Patients with RA who temporarily discontinued tofacitinib had similar safety events to those ...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
Conditions:   Rheumatoid Arthritis - Hand Joint;   Osteoarthritis Hand;   Pain;   Mobility Limitation;   Stiffness of Hand, Not Elsewhere Classified Interventions:   Other: Smartphone Application;   Other: Conventional treatment Sponsors:   University of Seville;   Fundación Pública Andaluza Progreso y Salud Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsHistory of mental health conditions and duration of the initial opioid prescription were associated with an increased risk of chronic opioid therapy among patients with RA.Key Points•Approximately a third of patients with RA are exposed to opioid analgesics.•Patients with RA and history of mental health disease, especially substance use disorders, who initiate opioid use have an increased risk of chronic opioid therapy.•This study provides insight in an underrepresented population of mainly male patients with RA.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
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