The effect of a single spinal manipulation on cardiovascular autonomic activity and the relationship to pressure pain threshold: a randomized, cross-over, sham-controlled trial

The autonomic nervous system interacts with the pain system. Knowledge on the effects of high velocity low amplitude spinal manipulations (SM) on autonomic activity and experimentally induced pain is limited. ...
Source: Chiropractic and Osteopathy - Category: Complementary Medicine Authors: Tags: Research Source Type: research

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This study was aimed to estimate the prevalence of chronic pain in different regions of China. Data on pain and its treatment were collected from 9357 participants using questionnaires and telephone-based interviews, from 31 regions of China. Gathered data were then coded into electronic data acquisition system and descriptive and inferential statistical analysis was performed. Out of 9298 participants, the ratio of chronic pain was 31.54% with the proportion of male having chronic pain (33.86%) was higher than that of female (29.53%). The average age of participants with pain (45.02 ± 15.07 years) was higher than f...
Source: Libyan Journal of Medicine - Category: General Medicine Tags: Libyan J Med Source Type: research
ConclusionsDespite published reports showing benefit for pain control in patients with BPA, the overall low quality, retrospective evidence included in this review highlights the need for a rigorous prospective study to further address this indication.
Source: Neuromodulation: Technology at the Neural Interface - Category: Biotechnology Authors: Tags: Review Article Source Type: research
https://www.painmedicinenews.com/Online-First/Article/01-20/Successful-Management-of-High-Spinal-Anesthesia-Following-C2-C3-Facet-Joint-Injection/57168?sub=FB91EF6AF8C99D4BDA1617412032C789116450929F4665EAF77A779E586D57&enl=true&dgid=U080859650&utm_source=enl&utm_content=2&utm_campaign=2020217&utm_medium=title Why are people still going IA?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
Altered pronociceptive and antinociceptive mechanisms are often implicated in painful conditions and have been increasingly studied over the past decade. For some painful conditions, alterations are well-established, but in populations with low back pain (LBP), there remains considerable debate whether these mechanisms are altered. The present systematic review aimed to address this issue by identifying studies assessing conditioned pain modulation (CPM) and/or temporal summation of pain (TSP) in patients with LBP, comparing with either a healthy control group or using a method with reference data available. Qualitative sy...
Source: Pain - Category: Anesthesiology Tags: Systematic Review and Meta-Analysis Source Type: research
Preventing and treating opioid dependence and withdrawal is a major clinical challenge, and the underlying mechanisms of opioid dependence and withdrawal remain elusive. We hypothesized that prolonged morphine exposure or chronic inflammation-induced μ-opioid receptor activity serves as a severe stress that elicits neuronal alterations and recapitulates events during development. Here, we report that Wnt signaling, which is important in developmental processes of the nervous system, plays a critical role in withdrawal symptoms from opioid receptor activation in mice. Repeated exposures of morphine or peripheral inflamma...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
Central neuropathic pain (CNP) after spinal cord injury (SCI) is debilitating and immensely impacts the individual. Central neuropathic pain is relatively resistant to treatment administered after it develops, perhaps owing to irreversible pathological processes. Although preemptive treatment may overcome this shortcoming, its administration necessitates screening patients with clinically relevant biomarkers that could predict CNP early post-SCI. The aim was to search for such biomarkers by measuring pronociceptive and for the first time, antinociceptive indices early post-SCI. Participants were 47 patients with acute SCI ...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
The amygdala is a key subcortical region believed to contribute to emotional components of pain. As opioid receptors are found in both the central (CeA) and basolateral (BLA) nuclei of the amygdala, we investigated the effects of morphine microinjection on evoked pain responses, pain-motivated behaviors, dopamine release in the nucleus accumbens (NAc), and descending modulation in rats with left-side spinal nerve ligation (SNL). Morphine administered into the right or left CeA had no effect on nerve injury–induced tactile allodynia or mechanical hyperalgesia. Right, but not left, CeA morphine produced conditioned pla...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
While working as a family therapist with kinship families, also known as grandparents raising their grandchildren, I came across families who were struggling with the ability to rebuild broken trust. Raising your grandchild (or another relative) brings with it attachment challenges you may not have faced when you raised your biological children. By “attachment” I am referring to the safety and comfort that develops, over time between a child and caregiver. For example, the bond between you and your children probably grew organically, beginning in utero, and continued to develop from the first day of their life...
Source: Psych Central - Category: Psychiatry Authors: Tags: Addictions Aging Caregivers Children and Teens Family Grief and Loss Parenting Substance Abuse Adverse Childhood Experience Attachment Bonding Child Development Grandfamily Grandparents grieving kinship family Source Type: news
The surgical robot industry is developing specialized products for neurosurgery, spinal surgery and other medical procedures that require greater precision, flexibility, and control than is possible with conventional techniques. Today, more than 5,000 surgical robots are installed worldwide – and that market is expected to grow at a double-digit rate over the next few years. For the designers of surgical robots, this presents both challenges and opportunities. The healthcare industry has discovered the numerous advantages of robotic surgery. For example, surgeons can benefit from having a higher viewing a...
Source: MDDI - Category: Medical Devices Authors: Tags: Materials Assembly and Automation Source Type: news
We report a case of Anaplastic Large Cell Lymphoma mimicking a psoas abscess in a 6-year-old girl which posed significant diagnostic challenges. She presented with a vague two-month history of anaemia, fevers and back and abdominal pain. Axial imaging including MRI suggested a diffuse, inflammatory lesion in the right psoas muscle and she was commenced on an intravenous antibiotic therapy regimen but with little improvement. An open biopsy was performed and histology confirmed Anaplastic Lymphoma Kinase 1 positive ALCL. To our knowledge, this is only the second case of ALCL with the tissues adjacent the psoas muscle as the...
Source: Journal of Pediatric Surgery Case Reports - Category: Surgery Source Type: research
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