Magnetized molecules used to monitor breast cancer

(Cancer Research UK) A new type of scan that involves magnetizing molecules allows doctors to see in real-time which regions of a breast tumor are active, according to research funded by Cancer Research UK and published in Proceedings of the National Academy of Sciences today. This is the first time researchers have demonstrated that this scanning technique, called carbon-13 hyperpolarized imaging, can be used to monitor breast cancer.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news

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DISCUSSION: For a diagnosis of primary breast cancer of the vulva, a thorough metastatic workup should be performed, with attention directed toward detecting a breast primary disease by results of the history, physical examination, and radiologic examination of the breasts mainly to help confirm that the vulvar lesion is the primary site as opposed to metastasis from a breast primary cancer and also for staging. Management of this rare entity is challenging because of a lack of specific guidelines, and treatment, therefore, is similar to that of breast cancer.Treatment should consist of an individualized combination of sur...
Source: The Permanente journal - Category: General Medicine Tags: Perm J Source Type: research
Quantitative ultrasound (QUS) techniques have been demonstrated to detect cell death in vitro and in vivo. Recently, multi-feature classification models have been incorporated into QUS texture-feature analysis methods to increase further the sensitivity and specificity of detecting treatment response in locally advanced breast cancer patients. To effectively incorporate these analytic methods into clinical applications, QUS and texture-feature estimations should be independent of data acquisition systems.
Source: Ultrasound in Medicine and Biology - Category: Radiology Authors: Tags: Original Contribution Source Type: research
Researchers from Tennessee have developed a navigation technique that employs...Read more on AuntMinnie.comRelated Reading: 3D micro-CT primed to revamp breast cancer imaging 3D printing may improve safety of upper GI surgery 3D-printed head customizes neurosurgery simulation How can 3D printing improve kidney cancer surgery? Portable gaming sensor enables 3D scans of elephantiasis
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
ConclusionsDelineation of post NACT excision cavity as POC for boost radiotherapy is safe. Clips serve as a good surrogate for CTV delineation in 75% patients.
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
ong Leem Chu The standardized uptake value (SUV), an indicator of the degree of glucose uptake in 18F-fluorodeoxyglucose positron emission tomography (FDG-PET), has been used for predicting the clinical behavior of malignant tumors. However, its characteristics have been insufficiently explored at the genomics level. Here, we aim to identify genomic signatures reflecting prognostic SUV characteristics in breast cancer (BRC). Through integrative genomic profiling of 3710 BRC patients, including 254 patients who underwent preoperative FDG-PET, we identified an SUV signature, which showed independent clinical utilit...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
Conclusion EORTC criteria and PERCIST had early predictive value to long-term outcome, but moderate value for pCR. Furthermore, PERCIST might show more potential than the EORTC criteria and conventional PET-based parameters to predict prognosis in breast cancer patients following two cycles of neoadjuvant chemotherapy. Video abstract: see http://links.lww.com/NMC/A162.
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: Original Articles Source Type: research
CONCLUSION: [18F]TFB was shown to be a promising hNIS-substrate in our model using the human MCF-7 breast cancer cell line mandating in vivo evaluations in xenografted studies and in patients. PMID: 32056515 [PubMed - in process]
Source: Current Cancer Drug Targets - Category: Cancer & Oncology Authors: Tags: Curr Cancer Drug Targets Source Type: research
Several indicators on pretreatment FDG-PET/CT scans can help predict overall...Read more on AuntMinnie.comRelated Reading: Biomarkers on PET, MRI show breast cancer risk FDG-PET/CT within a year of heart valve surgery looks safe FDG-PET/CT helps predict tuberculosis relapse 2 new PET tracers may best FDG in cancer imaging FDG-PET/CT aids in melanoma treatment assessment
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Breast MRI scans found six cases of breast cancer in high-risk women that had...Read more on AuntMinnie.comRelated Reading: AI boosts radiologists' mammography performance CEDM excels as presurgical diagnosis tool in large study Study supports interval MRI for likely benign findings PET/MRI tops MRI in breast lesion comparisons MRI finds breast cancer early in women with family history
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Conclusion: Kinetic parameters measured 2.5 weeks post-SABR in both single fraction and three fraction groups were indicative of response but only the single fraction protocol led to enhancement in the surrounding tissue. Our results also suggest that DCE-MRI one-week post-SABR may be too early for response assessment, at least for single fraction SABR, whereas 2.5 weeks appears sufficiently long to minimize confounding acute effects. PMID: 32021911 [PubMed]
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: Clin Transl Radiat Oncol Source Type: research
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