Update on weight-gain caused by antipsychotics: a systematic review and meta-analysis.

Update on weight-gain caused by antipsychotics: a systematic review and meta-analysis. Expert Opin Drug Saf. 2020 Jan 17;: Authors: Barton BB, Segger F, Fischer K, Obermeier M, Musil R Abstract Introduction: Antipsychotic-induced weight-gain (AIWG) is a very important, yet often neglected side-effect in the treatment with first and second generation antipsychotics. AIWG can increase the risk of developing metabolic syndrome, diabetes and cardiovascular disease. Meta-analyses mostly concentrate on AIWG in schizophrenic and bipolar patients, even though antipsychotics are prescribed off-label across many other diagnostic groups (e.g. anxiety disorders, depression, autistic disorder).Areas covered: Pub Med and Web of Science were systematically searched for RCTs reporting on AIWG with a sample size of ≥ 100 published between 2014 and 2019. All diagnoses and ages were included.Expert opinion: Inclusion criteria were fulfilled by 27 RCTs. All antipsychotics led to significantly more weight-gain (p
Source: Expert Opinion on Drug Safety - Category: Drugs & Pharmacology Tags: Expert Opin Drug Saf Source Type: research

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CONCLUSION: Our study expands the mutation spectrum of WSF1 mutations with three novel mutations. Homozygosity mapping may provide enrichment for molecular genetic analysis and early diagnosis of WS1 patients with incomplete phenotype, particularly in consanguineous pedigrees. PMID: 32938580 [PubMed - as supplied by publisher]
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research
CONCLUSION: Our study is important to emphasize that psychiatric disorders in DSD patients negatively affect the quality of life. Psychiatric support and counseling of multidisciplinary team are very important in DSD cases. PMID: 32938579 [PubMed - as supplied by publisher]
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research
This study aims to determine the incidence of T1D in children under the age of 15 years, living in Tlemcen in Northwest Algeria. METHODS: A retrospective study conducted on data of children (
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research
Publication date: Available online 17 September 2020Source: Journal of Anxiety DisordersAuthor(s): Hannah E. Frank, Emily Becker-Haimes, Lara S. Rifkin, Lesley A. Norris, Thomas H. Ollendick, Thomas M. Olino, Hilary E. Kratz, Rinad S. Beidas, Philip C. Kendall
Source: Journal of Anxiety Disorders - Category: Psychiatry Source Type: research
Conclusion The plasma C-peptide levels at 0 and 120 minutes in the MTT provide essential information for the clinical management of patients with type 2 diabetes mellitus. PMID: 32938850 [PubMed - in process]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Conclusion Snoring was shown to be a frequent pathophysiology in active workers. It was a health indicator for active workers, and especially in men, intervention for snoring may reduce the risk of developing lifestyle-related diseases. PMID: 32938849 [PubMed - in process]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Publication date: Available online 18 September 2020Source: Trends in Food Science &TechnologyAuthor(s): Pei Gee Yap, Chee Yuen Gan
Source: Trends in Food Science and Technology - Category: Food Science Source Type: research
Women, patients younger than 30 years have higher rates of depression
Source: The Doctors Lounge - Psychiatry - Category: Psychiatry Tags: Dermatology, Family Medicine, Gynecology, Internal Medicine, Pharmacy, Psychiatry, Institutional, Source Type: news
Publication date: Available online 18 September 2020Source: Physiology &BehaviorAuthor(s): Amir Hossien Mehrsafar, Miguel Angel Serrano Rosa, Ali Moghadam Zadeh, Parisa Gazerani
Source: Physiology and Behavior - Category: Physiology Source Type: research
CONCLUSIONS: Since anxiety and hyperactivity were predictors of nomophobia according to the study, adolescents with attention deficit hyperactivity disorder or anxiety disorder should be examined for nomophobia as well. Key points Nomophobia levels of internalising and externalising disordered groups did not differ. Internalising group had higher scores in two sub-dimensions of nomophobia. All anxiety and depression symptoms correlated with nomophobia. Hyperactivity and oppositional symptoms correlated with nomophobia. Total anxiety and hyperactivity were predictors of nomophobia. PMID: 32940094 [PubMed - as supplied by publisher]
Source: International Journal of Psychiatry in Clinical Practice - Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research
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