Determination of residual fipronil and its metabolites in food samples: A review

Publication date: Available online 20 January 2020Source: Trends in Food Science & TechnologyAuthor(s): Xianjiang Li, Wen Ma, Hongmei Li, Qinghe Zhang, Zhiyong MaAbstractBackgroundFipronil is an effective phenylpyrazole insecticide commonly used in agriculture for pest control. In creature, fipronil could be metabolized to several more toxic metabolites. These compounds can contaminate or migrate into foodstuffs and potentially pose danger to human health.Scope and approachThis review aims to provide a comprehensive review on the determination methods used for fipronil and its metabolites, including gas chromatography-electron capture detector (GC-ECD), gas chromatography-mass spectrometry (GC-MS), liquid chromatography-ultraviolent detector (LC-UV), liquid chromatography-mass spectrometry (LC-MS) and other fast screening techniques. Detailed information regarding sample preparation, separation and detection condition, and methodological result is provided.Key findingsGC-ECD is quite fit for these fluorine-rich analytes, GC-MS method has good selectivity and sensitivity, but they take long time for separation. LC based methods have advantage in fast separation, but LC-UV method isn't satisfactory for low sensitivity, LC-MS is the most preferred technique at the expense of expensive instrument. At last, new directions and perspectives are discussed.
Source: Trends in Food Science and Technology - Category: Food Science Source Type: research