Cost-effectiveness of HCV Testing in Community Pharmacies Cost-effectiveness of HCV Testing in Community Pharmacies

Is pharmacy-based targeted testing for HCV a cost-effective approach?Journal of Viral Hepatitis
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

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Publication date: Available online 17 February 2020Source: Antiviral ResearchAuthor(s): Yingying Dou, Diahann T.S.L. Jansen, Aniek van den Bosch, Robert A. de Man, Nadine van Montfoort, Can Araman, Sander I. van Kasteren, Gijs G. Zom, Willem-Jan Krebber, Cornelis J.M. Melief, Andrea M. Woltman, Sonja I. BuschowAbstractSynthetic long peptide (SLP) vaccination is a promising new treatment strategy for patients with a chronic hepatitis B virus (HBV) infection. We have previously shown that a prototype HBV-core protein derived SLP was capable of boosting CD4+ and CD8+ T cell responses in the presence of a TLR2-ligand in chroni...
Source: Antiviral Therapy - Category: Virology Source Type: research
Using a gene sequencing approach, this study examined the gut microbiota profile of patients with hepatitis B virus-induced chronic liver disease compared with healthy controls.Journal of Viral Hepatitis
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: Gastroenterology Journal Article Source Type: news
What is the impact of delaying treatment for different populations of people living with hepatitis C? The authors present a clinical decision tool for informing treatment timing decisions.Liver International
Source: Medscape General Surgery Headlines - Category: Surgery Tags: Gastroenterology Journal Article Source Type: news
In this study, a rapid and precise method based on ultra-high performance liquid chromatography (UPLC) combined with an Orbitrap mass spectrometer (UPLC–Orbitrap–MS/MS) was established in both positive- and negative-ion modes to rapidly identify various chemical components in the tubers of G. conopsea for the first time. Finally, a total of 91 compounds, including 17 succinic acid ester glycosides, 9 stilbenes, 6 phenanthrenes, 19 alkaloids, 11 terpenoids and steroids, 20 phenolic acid derivatives, and 9 others, were identified in the tubers of G. conopsea based on the accurate mass within 3 ppm error. ...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Bone Marrow Transplantation, Published online: 18 February 2020; doi:10.1038/s41409-020-0823-7Hepatitis E virus is an infrequent but potentially serious infection in allogeneic hematopoietic stem cell transplant recipients
Source: Bone Marrow Transplantation - Category: Hematology Authors: Source Type: research
Bone Marrow Transplantation, Published online: 18 February 2020; doi:10.1038/s41409-020-0833-5A prospective trial of vaccine to prevent hepatitis B virus reactivation after hematopoietic stem cell transplantation
Source: Bone Marrow Transplantation - Category: Hematology Authors: Source Type: research
Microsporidia are found worldwide and both vertebrates and invertebrates can serve as hosts for these organisms. While microsporidiosis in humans can occur in both immune competent and immune compromised hosts, it has most often been seen in the immune suppressed population, e.g., patients with advanced HIV infection, patients who have had organ transplantation, those undergoing chemotherapy, or patients using other immune suppressive agents. Infection can be associated with either focal infection in a specific organ (e.g., keratoconjunctivitis, cerebritis, or hepatitis) or with disseminated disease. The most common presen...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
In this study, we assessed whether there were any survival advantages with a combination treatment of intravenousN-acetylcysteine (NAC) and prednisone over prednisone alone in those with severe alcoholic hepatitis [discriminant function (DF)  ≥ 32].Patients and MethodsBetween January 1, 2013, and February 28, 2019, we identified 68 patients (mean age 47.2  years ± 10.1, 57% women, 65% cirrhosis, MELD score 28.1 ± 6.6) with alcoholic hepatitis, and of those, 21 (31%) received prednisone and 47 (69%) received prednisone + NAC. Lille score &g...
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
ConclusionsTransplanting kidneys from HCV-viremic donors into HCV-uninfected recipients increased quality-adjusted life expectancy and reduced costs compared with a strategy of transplanting kidneys from HCV-unexposed donors.
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
[International Network on Hepatitis in Substance Users] INHSU Africa, a historic meeting of researchers, policy makers, politicians and advocates to plan for the elimination of viral hepatitis for people who use drugs has commenced today with a planning session for advocates across the African region.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
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