Fas Ligand Enhances Apoptosis of Human Lung Cancer Cells Cotreated with RIG-I-Like Receptor Agonist and Radiation.

CONCLUSION: In summary, the present study indicated that upregulated Fas expression following cotreatment with Poly(I:C)-HMW and IR was responsive to FasL-induced apoptosis, and combination of RLR agonist, IR, and FasL could be a potential promising cancer therapy. PMID: 31951181 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31951181?dopt=Abstract

Source: Current Cancer Drug Targets - January 14, 2020 Category: Cancer & Oncology Authors: Sato Y, Yoshino H, Tsuruga E, Kashiwakura I Tags: Curr Cancer Drug Targets Source Type: research