The potential targets and mechanisms of a carbazole and pyrazole containing anticancer compound.

CONCLUSION: VUGX01 can effectively block proliferation and induce apoptosis of certain type of cancer cells, even it's predicted by high LASSO score, but it is not an effective RTKs inhibitor, it may inhibit cell growth through acting as a novel ligand to one or several GPCRs. PMID: 31951182 [PubMed - as supplied by publisher]
Source: Current Cancer Drug Targets - Category: Cancer & Oncology Authors: Tags: Curr Cancer Drug Targets Source Type: research