A comprehensive contribution of genetic variations of the insulin-like growth factor 1 signalling pathway to stroke susceptibility

The insulin-like growth factor (IGF)-1 signalling pathway has been implicated in the pathogenesis of atherosclerosis; however, the mechanism underlying its role in stroke remains unexplained. Herein, we aimed to explore the effects of genetic polymorphisms in the IGF1 pathway on stroke in the Chinese Han population.

Source: Atherosclerosis - January 17, 2020 Category: Cardiology Authors: Yingshui Yao, Hui Zhu, Lijun Zhu, Zhengmei Fang, Yao Fan, Chunlan Liu, Yuanrui Tian, Yan Chen, Wuzhuang Tang, Zhanyun Ren, Jie Li, Song Yang, Yanchun Chen, Xianghai Zhao, Chong Shen Source Type: research