Programmed death ligand-1 expression is associated with stage and histological grade of parotid carcinoma.

Conclusions: PD-L1 expression was positive in approximately 50% of high- grade carcinomas, which was similar to the level in head and neck squamous cell carcinoma. In patients with other cancers, it has been reported that an anti-PD-1 monoclonal antibody was more effective against tumors with higher PD-L1 expression. Therefore, it could be a possible new therapeutic option for patients with highly malignant parotid tumors that have a poor prognosis.
PMID: 31944154 [PubMed - as supplied by publisher]

Source: Acta Oto-Laryngologica - January 15, 2020 Category: ENT & OMF Authors: Higashino M, Kawata R, Nishikawa S, Terada T, Haginomori SI, Kurisu Y, Hirose Y Tags: Acta Otolaryngol Source Type: research