Extension of survival in bilaterally adrenalectomized mice by implantation of SF-1/Ad4BP-induced steroidogenic cells.

In conclusion, implantation of steroidogenic cells derived from ADSCs into bAdx mice increased the basal plasma corticosterone level and extended the survival of bAdx mice, suggesting the capability of restoring steroidogenic cells by cell transplantation therapy for adrenal insufficiency. PMID: 31950150 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31950150?dopt=Abstract

Source: Endocrinology - January 16, 2020 Category: Endocrinology Authors: Tanaka T, Aoyagi C, Mukai K, Nishimoto K, Kodama S, Yanase T Tags: Endocrinology Source Type: research