Over expression of long non-coding RNA uc.187 induces preeclampsia-like symptoms in pregnancy rats.

CONCLUSIONS: Taken together, our study revealed that uc.187 was negatively correlated to trophoblastic cell invasion, and over-expression of uc.187 could induce PE-like symptoms in a pregnant rat model by affecting the distribution of β-catenin in the cytoplasm and nucleus.
PMID: 31950140 [PubMed - as supplied by publisher]

Source: American Journal of Hypertension - January 16, 2020 Category: Cardiology Authors: Huang J, Qian Y, Cheng Q, Yang J, Ding H, Jia R Tags: Am J Hypertens Source Type: research