Dysregulation of BDNF/TrkB signaling mediated by NMDAR/Ca2+/calpain might contribute to postoperative cognitive dysfunction in aging mice

Postoperative cognitive decline (POCD) is a recognized clinical phenomenon characterized by cognitive impairments in patients following anesthesia and surgery, yet its underlying mechanism remains unclear. Bra...

Source: Journal of Neuroinflammation - January 16, 2020 Category: Neurology Authors: Li-Li Qiu, Wei Pan, Dan Luo, Guang-Fen Zhang, Zhi-Qiang Zhou, Xiao-Yun Sun, Jian-Jun Yang and Mu-Huo Ji Tags: Research Source Type: research