Esophageal Melanocytosis in a Patient With Gastroesophagheal Reflux Disease

A 40-year-old man, ex-smoker with a history of type 2 diabetes mellitus and previous Helicobacter pylori associated gastritis, presented with heartburn, globus sensation, and early satiety. An esophagogastroduodenoscopy was performed and noted multiple flat hyperpigmented areas in the mid-esophagus (Figures A, arrows and B). Targeted biopsies of the esophageal lesion showed scattered squamous cells and melanocytes containing brownish melanin pigments in the basal portion of the esophageal squamous mucosa (Figure C, arrows).
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Tags: Image of the month Source Type: research