Decreasing the Peril of Antimicrobial Resistance Through Enhanced Health Literacy in Outpatient Settings: An Underrecognized Approach to Advance Antimicrobial Stewardship
We describe Four Core Elements of Enhancing AMS Health Literacy in the Outpatient Setting, utilizing the Centers for Disease Control and Preve ntion’s framework: (1) leadership commitment, (2) intervention/action, (3) tracking/reporting, and (4) education/expertise. We call upon leaders in outpatient settings to embrace this approach to curb inappropriate antimicrobial use.
Conclusions: A heterogeneous dispersion in the general practitioners' attitudes was found. Continuous professional development (CPD) of general practitioners in the topic of antibiotic resistance could be of great importance. Orv Hetil. 2020; 161(9): 330-339. PMID: 32088975 [PubMed - in process]
ConclusionsOur data suggest that fosfomycin has good effect against mucoid and non-mucoid strains of P. aeruginosa and automated systems can be implemented in clinical microbiology laboratories to assess fosfomycin with rapid and reproducible results.
ConclusionsIn this study, the majority of MRSE belonged to cluster II domain of CC2. The ST59-IV was a dominant clone among isolates recovered from hospital personnel. Determination of new MLST types confirmed the genetic diversity of these isolates. These observations highlight the need to review the infection control strategies to reduce the carriage of MRSE among hospital personnel.
ConclusionsAn alarming rate of phenotypic resistance was observed in this study. Many isolates were positive for the screened resistance genes. According to the phylogenetic background, most resistant isolates belonged to the commensal phylo-types, representing significant role of commensal strains as a source of resistance genes. These findings highlight the role of pigeon as disseminator of resistant E. coli strains.
Publication date: Available online 22 February 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Marisa Haenni, Farid El Garch, Christine Miossec, Jean-Yves Madec, Didier Hocquet, Benoit Valot
Empirical gonorrhea treatment at initial diagnosis reduces onward transmission. However, increasing resistance to multiple antibiotics may necessitate waiting for culture-based diagnostics to select an effective treatment. There is a need for same-day culture-free diagnostics that identify infection and detect antimicrobial resistance. We investigated if Nanopore sequencing can detect sufficient Neisseria gonorrhoeae DNA to reconstruct whole genomes directly from urine samples. We used N. gonorrhoeae-spiked urine samples and samples from gonorrhea infections to determine optimal DNA extraction methods that maximize the amo...
ICFR Abstract Bacterial resistance to the therapeutical drugs has been a serious issue over the last decades. In fact, the quick development of resistance mechanisms by the microorganisms has been fatal for millions of people around the world, turning into a public health issue. The major cause for the resistance mechanisms is the overuse of antimicrobials. European countries try to implement mechanisms to overcome antimicrobial resistance in the community through the rational use of antimicrobials. The scientific community has been exhaustively dedicated to the discovering of new, safer and efficient drugs, being...
ConclusionsThe prospective surveillance and active screening for VRE was very useful to determine the true ratio of intestinal colonization to infection and thus helps to shape infection control management.
Publication date: Available online 21 February 2020Source: American Journal of Infection ControlAuthor(s): Aleksa Despotovic, Branko Milosevic, Ivana Milosevic, Nikola Mitrovic, Andja Cirkovic, Snezana Jovanovic, Goran StevanovicBackgroundAcquisition of Hospital-acquired infections (HAIs) in intensive care units (ICUs) predispose patients to higher mortality rates and additional adverse events. Serbian adult ICUs are rarely investigated for HAIs. The aim of this study was to look into HAIs in an adult ICU and identify risk factors for acquisition of HAIs and mortality.MethodsThis retrospective study included 355 patients h...