Antidepressant and neurocognitive effects of serial ketamine administration versus ECT in depressed patients

ConclusionsDue to its pro-cognitive effects and faster antidepressant effect, serial ketamine administration might be a more favorable short-term treatment option than ECT.LimitationsAs this research employed a naturalistic study design, patients were not systematically randomized, there was no control group and patients received concurrent and partially changing medications during treatment.Clinical trials registrationFunctional and Metabolic Changes in the Course of Antidepressive Treatment, https://clinicaltrials.gov/ct2/show/NCT02099630, NCT02099630.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research