Active and Unidirectional Acceleration of Biaryl Rotation by a Molecular Motor.

Active and Unidirectional Acceleration of Biaryl Rotation by a Molecular Motor. Angew Chem Int Ed Engl. 2020 Jan 15;: Authors: Uhl E, Mayer P, Dube H Abstract Light driven molecular motors possess immense potential as central driving units for future nanotechnology. Integration into larger molecular setups and transduction of their mechanical motions represents the current frontier of research. Here we report on an integrated molecular machine setup allowing to transmit potential energy from a motor unit unto a remote receiving entity. The setup consists of a motor unit connected covalently to a distant and sterically strongly encumbered biaryl receiver. By action of the motor unit single bond rotation of the receiver is strongly accelerated and forced to proceed unidirectionally. The transmitted potential energy is directly measured as the extent to which energy degeneration is lifted in the thermal atropisomerization of this biaryl. Energy degeneracy is reduced by more than 1.6 kcal/mol and rate accelerations of several orders of magnitude in terms of rate constants are achieved. PMID: 31943681 [PubMed - as supplied by publisher]
Source: Angewandte Chemie - Category: Chemistry Authors: Tags: Angew Chem Int Ed Engl Source Type: research