Competitive glucose metabolism as a target to boost bladder cancer immunotherapy

Nature Reviews Urology, Published online: 17 January 2020; doi:10.1038/s41585-019-0263-6An energetic interplay between tumour and immune cells leads to metabolic competition in the tumour ecosystem, an effect that could be targeted to boost immune checkpoint inhibition. In this Review, the authors discuss cancer cell and immune cell metabolism and consider the potential therapeutic targets within these processes.
Source: Nature Reviews Urology - Category: Urology & Nephrology Authors: Source Type: research