More Pronounced Infection of Highly Pathogenic Avian Influenza (HPAI) H5N6 Virus in Chickens Compared with Pekin Ducks

Publication date: January 2020Source: Journal of Comparative Pathology, Volume 174Author(s): S.A. Bergervoet, S. Vreman, R. Zwart, N. Stockhofe-Zurwieden, N. Beerens
Source: Journal of Comparative Pathology - Category: Pathology Source Type: research

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Source: RxList - New and Updated Drug Monographs - Category: Drugs & Pharmacology Source Type: news
Publication date: 1 May 2020Source: Sensors and Actuators B: Chemical, Volume 310Author(s): Fanwei Luo, Chao Long, Zhen Wu, Huayu Xiong, Miaomiao Chen, Xiuhua Zhang, Wei Wen, Shengfu WangAbstractElectrochemiluminescence (ECL) has been widely used in detection of biomarkers. However, the lacks of efficient ECL emitter and anti-interference ability limit its clinical application. Here, a sensitive ECL immunosensor was proposed for H9N2 avian influenza virus (H9N2 AIV) detection using functional silica nanospheres as signal carriers and magnetic nanobeads (MBs) as capture carriers. Functional silica nanospheres were prepared ...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
In December 2017, an influenza A(H9N2) virus (B51) was isolated from migratory waterfowl in Hubei Province, China. Phylogenetic analysis demonstrated that B51 is a novel reassortant influenza virus containing segments from human H7N4 virus and North American wild bird influenza viruses. This suggest that B51 has undergone multiple reassortment events.
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Source: RxList - New and Updated Drug Monographs - Category: Drugs & Pharmacology Source Type: news
ark Yeo In July 2018, a novel avian influenza virus (A/Mandarin duck/South Korea/KNU18-12/2018(H11N9)) was isolated from Mandarin ducks in South Korea. Phylogenetic and molecular analyses were conducted to characterize the genetic origins of the H11N9 strain. Phylogenetic analysis indicated that eight gene segments of strain H11N9 belonged to the Eurasian lineages. Analysis of nucleotide sequence similarity of both the hemagglutinin (HA) and neuraminidase (NA) genes revealed the highest homology with A/duck/Kagoshima/KU57/2014 (H11N9), showing 97.70% and 98.00% nucleotide identities, respectively. Additionally, inte...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Exosomes, the extracellular vesicles that contain functional proteins and RNAs, regulate cell-cell communication. Recently, our group reported that levels of various microRNAs (miRNAs) in bronchoalveolar lavage fluid exosomes were highly increased in influenza virus-infected mice and that one of those miRNAs, miR-483-3p, was involved in the potentiation of the innate immune responses to influenza virus infection in mouse type II pneumocytes. Here, we evaluated exosomal miR-483-3p levels in the serum of influenza virus-infected mice and found that miR-483-3p levels were significantly increased during infection with a highly...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
In February 2020 the nature of the 2019-nCoV outbreak is still slowly coming into focus but it appears to be acting more like bad pandemic influenza (efficient spread, overall lower mortality) than like SARS (less efficient spread, overall higher mortality). Anthony Fauci, MD, of the US National Institute of Allergy and Infectious Diseases (NIAID) discusses the latest developments with JAMA Editor in Chief Howard Bauchner. Coronavirus Resource Center
Source: JAMA Author Interviews - Category: General Medicine Authors: Source Type: podcasts
Abstract International travel-related nonpharmaceutical interventions (NPIs), which can include traveler screening, travel restrictions, and border closures, often are included in national influenza pandemic preparedness plans. We performed systematic reviews to identify evidence for their effectiveness. We found 15 studies in total. Some studies reported that NPIs could delay the introduction of influenza virus. However, no available evidence indicated that screening of inbound travelers would have a substantial effect on preventing spread of pandemic influenza, and no studies examining exit screening were found....
Source: Emerging Infectious Diseases - Category: Infectious Diseases Authors: Tags: Emerg Infect Dis Source Type: research
Abstract There were 3 influenza pandemics in the 20th century, and there has been 1 so far in the 21st century. Local, national, and international health authorities regularly update their plans for mitigating the next influenza pandemic in light of the latest available evidence on the effectiveness of various control measures in reducing transmission. Here, we review the evidence base on the effectiveness of nonpharmaceutical personal protective measures and environmental hygiene measures in nonhealthcare settings and discuss their potential inclusion in pandemic plans. Although mechanistic studies support the po...
Source: Emerging Infectious Diseases - Category: Infectious Diseases Authors: Tags: Emerg Infect Dis Source Type: research
The objective of these mitigation measures is to reduce transmission, thereby delaying the epidemic peak, reducing the size of the epidemic peak, and spreading cases over a longer time to relieve pressure on the healthcare system. We conducted systematic reviews of the evidence base for effectiveness of multiple mitigation measures: isolating ill persons, contact tracing, quarantining exposed persons, school closures, workplace measures/closures, and avoiding crowding. Evidence supporting the effectiveness of these measures was obtained largely from observational studies and simulation studies. Voluntary isolation at home ...
Source: Emerging Infectious Diseases - Category: Infectious Diseases Authors: Tags: Emerg Infect Dis Source Type: research
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