Systematic Evaluation of Levodopa Effect on Visual Improvement in Amblyopia: A Meta-analysis

This study aims to evaluate the effectiveness of levodopa as a therapeutic drug in the treatment of children and adults with amblyopia. Methods We performed a systematic review and meta-analysis with randomized controlled trials of levodopa and placebo in the treatment of amblyopia. All data were identified and extracted from the PubMed, EMBASE, Cochrane libraries, and the Chinese knowledge resource integration database. Results After screening the literature and evaluating the quality, 11 studies met the criteria from 308 studies. The mean difference of LogMAR visual acuity between levodopa and the placebo group was −0.1031 (95% confidence interval, −0.11 to −0.09; P
Source: Clinical Neuropharmacology - Category: Neurology Tags: Review Article Source Type: research