Effect of Smoking Cessation on the Pharmacokinetics and Pharmacodynamics of Clopidogrel after PCI: The Smoking Cessation Paradox Study.

CONCLUSION:  Smoking cessation in clopidogrel-treated patients after PCI is associated with increased platelet reactivity and greater risk of HPR. Alternative P2Y12 inhibitors may be considered in selected patients who stop smoking after PCI.
PMID: 31940672 [PubMed - as supplied by publisher]

Source: Thrombosis and Haemostasis - January 14, 2020 Category: Hematology Authors: Ramotowski B, Gurbel PA, Tantry U, Bracha JS, Karaźniewicz-Łada M, Lewandowski Z, Budaj A Tags: Thromb Haemost Source Type: research