Commentary: Can we truly get Staphylococcus aureus infectivity of biologic heart valve conduits to slip away?

In this issue of the Journal, Ditkowski and colleagues,1 through an elaborate series of in  vitro experiments, present compelling evidence for the prominent role of platelets and fibrinogen in the development of Staphylococcus aureus infective endocarditis (IE) of biologic heart valve conduits.1 Specifically, they focus on the complex interaction of Staphylococcus clumping factor A (ClfA ), fibrinogen, platelet αIIbβ3 receptors, and platelet adenosine diphosphate receptors as modulators of bacterial adhesion on various graft tissues.
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Commentary Source Type: research