Evaluation of CD4+CD25+FOXP3+ regulatory T cells and FOXP3 mRNA in premature ovarian insufficiency.
Conclusions: Our study suggested that POI may be associated with an abrogated function of circulating CD4+CD25+FOXP3+ Treg cells and a decreased level of FOXP3 gene expression. However, these results require further investigation.
PMID: 31939315 [PubMed - as supplied by publisher]
Source: Climacteric - Category: Geriatrics Authors: Xiong J, Tan R, Wang W, Wang H, Pu D, Wu J Tags: Climacteric Source Type: research