Evolution of Api m10 Specific IgE and IgG4 After One Year of Bee Venom Immunotherapy.

Conclusions. Although there was no increase in Api m10 sIgG4 levels after 1 year bVIT, we did not observe relevant differences in other outcomes between patients with predominant Api m1 or Api m10 sensitization. PMID: 31939631 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

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Conditions:   Hymenoptera Venom Allergy;   Antihypertensive Treatment Intervention:   Drug: Insect Venom Sponsor:   Medical University of Graz Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSION: Clinicians should continue to discuss avoidance as a viable option for long-term peanut allergy management and empower patients to differentiate relevant situations in which accidental reactions might occur. PMID: 32001367 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Ann Allergy Asthma Immunol Source Type: research
This article provides highlights of the clinically impactful original studies and reviews published in The Journal of Allergy and Clinical Immunology: In Practice in 2019 on the subjects of anaphylaxis, asthma, dermatitis, drug allergy, food allergy, immunodeficiency, immunotherapy, rhinitis/sinusitis, and urticaria/angioedema/mast cell disorders. Within each topic, practical aspects of diagnosis and management are emphasized. Treatments discussed include lifestyle modifications, allergen avoidance therapy, positive and negative effects of pharmacologic therapy, and various forms of immunologic and desensitization manageme...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
We have prepared a case that highlights the relationship between a patient ’s emotional state and the potential for systemic allergic reactions including anaphylaxis in a heretofore stable patient receiving maintenance subcutaneous allergen immunotherapy (SCIT) for treatment of allergic rhinoconjunctivitis (ARC) and mild persistent asthma.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Challenging Clinical Cases Source Type: research
os PS PMID: 31972295 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Ann Allergy Asthma Immunol Source Type: research
Cow's milk (CM) is a common allergen present in immunoglobulin E (IgE)-mediated food allergy in children. The management of CM allergy (CMA) requires the replacement of milk protein with alternative protein and calcium sources. Extensively hydrolyzed formulas (eHFs) are alternative, hypoallergenic formulas that are recommended as standards for children with CMA.1 IgE-mediated immediate reactions to eHFs, such as life-threatening anaphylaxis, rarely occur.2 Patients with hyperresponsiveness to eHFs may be at a high risk because they are on a complete elimination diet.
Source: Pediatrics and Neonatology - Category: Perinatology & Neonatology Authors: Tags: Letter to the Editor Source Type: research
CONCLUSION: Data are emerging to confirm our clinical experience that many food-allergic patients experience stereotypical symptoms following allergen exposure, both in the community and at supervised oral food challenge, in a manner that varies from one patient to another. Integrating datasets from different cohorts and applying unbiased machine-learning analyses may demonstrate specific food allergy endotypes, in a similar way to asthma. Whether this results in improvements in patient management (e.g. through facilitating risk stratification or impacting on the decision to prescribe EAI and, perhaps, the number of device...
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Ann Allergy Asthma Immunol Source Type: research
Publication date: March 2020Source: Biomedicine &Pharmacotherapy, Volume 123Author(s): Abdolreza Esmaeilzadeh, Safa Tahmasebi, Seyyed Shamsadin AthariAbstractDespite the current advancements, cancer treatment approaches have limitations restricting their cure rate. Immunotherapy techniques are among novel and promising cancer therapeutic approaches. Therapeutic antibodies and adoptive cell therapy (ACT) are the main branches of immunotherapy. T lymphocytes and genetically engineered cells are among important cells which can be used in ACT. This review has focused on recent advances in engineered cell-based immunotherap...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Abstract Shrimp allergy, a common form of food allergy is an adverse immunological response to shrimp proteins. BALB/c mice was sensitized by an adjuvant free oral administration of purified tropomyosin, from Metpenaeus dobsonii to characterize intestinal histological responses and immunological protein recognition pattern as it is unpractical in human subjects. Sensitized mice with higher dose of tropomyosin expressed symptoms of anaphylaxis including puffiness around eyes and snout, no activity, tremor and convulsion after challenge. The responses of high level of sera IgE, tropomyosin specific IgE and histamine...
Source: Immunology Letters - Category: Allergy & Immunology Authors: Tags: Immunol Lett Source Type: research
Peanut allergy affects 1-2% of individuals in the United States, and is increasing in prevalence.1-4 Although there is accumulating data on immunotherapy for peanut allergy,5-8 the cornerstone of management remains strict avoidance of peanut protein, maintenance of an emergency action plan and prompt use of epinephrine to treat systemic reactions in case of an accidental exposure, which occurs in up to 12-15% of peanut-allergic individuals annually.9,10 Peanut allergy significantly impacts quality of life,11 as it is typically lifelong, is the leading cause of food-induced anaphylaxis in children, and the leading cause of ...
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research
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