Chattering-free hybrid adaptive neuro-fuzzy inference system-particle swarm optimisation data fusion-based BG-level control

In this study, a closed-loop control scheme is proposed for the glucose–insulin regulatory system in type-1 diabetic mellitus (T1DM) patients. Some innovative hybrid glucose–insulin regulators have combined artificial intelligence such as fuzzy logic and genetic algorithm with well known Palumbo model to regulate the blood glucose (BG) level in T1DM patients. However, most of these approaches have focused on the glucose reference tracking, and the qualitative of this tracking such as chattering reduction of insulin injection has not been well-studied. Higher-order sliding mode (HoSM) controllers have been employed to attenuate the effect of chattering. Owing to the delayed nature and non-linear property of glucose–insulin mechanism as well as various unmeasurable disturbances, even the HoSM methods are partly successful. In this study, data fusion of adaptive neuro-fuzzy inference systems optimised by particle swarm optimisation has been presented. The excellent performance of the proposed hybrid controller, i.e. desired BG-level tracking and chattering reduction in the presence of daily glucose-level disturbances is verified.
Source: IET Systems Biology - Category: Biology Source Type: research

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ConclusionThere was a negative correlation between cost of care and glycemic control. Lower cost of care was associated with high burden of psychosocial illness and poor quality of life.
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
CONCLUSIONS: There has been a marked reduction in microvascular complications in Waikato youth and young adults with type 1 diabetes, but the reasons for the reduction are not clear given there has been no significant improvements in glycaemic control. PMID: 32078599 [PubMed - in process]
Source: New Zealand Medical Journal - Category: General Medicine Tags: N Z Med J Source Type: research
Conclusion: Changes in the choroid may occur before the development of diabetic retinopathy and seem to progress with increasing diabetes mellitus duration despite the absence of diabetic retinopathy and without associated retina thickening. Choroidal thickness could be valuable for screening in diabetic children.
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
Conclusion Applying diabetes treatment information from the National Health and Nutrition Examination Survey, as formulated in our treatment-based algorithm, may better identify type 1 and type 2 diabetes cases and thus prevent the specific biases imposed by conventional approaches which include the age of diabetes diagnosis as an initial criterion for diabetes type classification.
Source: Cardiovascular Endocrinology - Category: Cardiology Tags: Original Articles Source Type: research
Publication date: Available online 21 February 2020Source: Life SciencesAuthor(s): Yu-pu Liu, Shui-jin Shao, Hai-dong GuoAbstractDiabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus that affects approximately half of patients with diabetes. Current treatment regimens cannot treat DPN effectively. Schwann cells (SCs) are very sensitive to glucose concentration and insulin, and closely associated with the occurrence and development of type 1 diabetic mellitus (T1DM) and DPN. Apoptosis of SCs is induced by hyperglycemia and is involved in the pathogenesis of DPN. This review considers the patholo...
Source: Life Sciences - Category: Biology Source Type: research
No abstract available
Source: Nursing - Category: Nursing Tags: Department: COMMUNITY CARE Source Type: research
Condition:   Type 1 Diabetes Intervention:   Sponsor:   Jannet Svensson Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Type1diabetes Intervention:   Behavioral: Residential camp Sponsor:   University of Texas Southwestern Medical Center Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Type 1 Diabetes Intervention:   Sponsor:   Jannet Svensson Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Type1diabetes Intervention:   Behavioral: Residential camp Sponsor:   University of Texas Southwestern Medical Center Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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