This Year ’s Flu Season Got Off to a Strange Start. What Does That Mean for the Months Ahead?

Flu season is always unpredictable. Different viral strains circulate each year, which makes forecasting the disease’s spread—and formulating the annual flu vaccine—an educated guessing game. Even so, the 2019-2020 flu season has been particularly unusual. Influenza B, the viral strain that usually circulates toward the end of flu season, instead emerged first this year, shifting usual transmission patterns. A vaccine mismatch and reduced immunity to influenza B may have contributed to the early and severe start of this flu season. What does that mean for the months ahead? TIME asked Lynnette Brammer, an epidemiologist who leads domestic surveillance for the U.S. Centers for Disease Control and Prevention (CDC)’s influenza division. What’s the difference between influenza A and B? Influenza A and B are the two primary strains of the virus that cause illness in humans. They both cause classic flu symptoms such as fever, cough, runny nose, chills, body aches and fatigue, and it’s nearly impossible to tell which one you have without a lab test, Brammer says. Influenza A viruses are the only type known to cause pandemics, because they change rapidly and affect both humans and animals. Influenza B is slower-adapting and typically present only in humans. Within each type, there are further subcategories. Influenza A subtypes are categorized by the combination of proteins on the virus’ surface; the two most common in humans are H1N1 and H3N...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Infectious Disease Source Type: news

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Authors: Wieland U, Oellig F, Kreuter A Abstract Anal intraepithelial neoplasia (AIN) and 89-100% of anal cancers are caused by persistent infections with high-risk (HR) human papillomaviruses (HPV). In HIV-positive patients, anal HPV infection and AIN are very common and these patients have a greatly increased risk of developing anal cancer. However, a continuous increase in the incidence of anal cancer has also been observed in the general population in recent decades. AIN can clinically present in diverse manners. In HIV-positive patients AIN can be hidden in condylomas. Furthermore, 3-14% of high-grad...
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research
Conclusions: Endometrial myomectomy is a feasible choice for treatment of fibroids during CS, and, basing on our results could be an alternative to traditional cesarean subserosal myomectomy. PMID: 32064967 [PubMed - as supplied by publisher]
Source: Journal of Investigative Surgery - Category: Surgery Tags: J Invest Surg Source Type: research
In this study, we aimed to investigate the degree of mosaicism present in villi by a combination of three different methods, namely conventional karyotyping following culture, multiplex ligation-dependent probe amplification (MLPA) and fluorescence in situ hybridization (FISH), with a view to exploring the incidence of selective growth of mosaic CV cells during the process of culture for conventional karyotyping. CV samples were obtained from 207 patients with early spontaneous miscarriage (ESM). There were 56 (56/207, 27.1%) samples with mosaic chromosome detected by FISH based on four or five types of probes in this stud...
Source: Molecular and Cellular Probes - Category: Molecular Biology Source Type: research
This study addressed a research gap about whether improved nutrition during pregnancy and early childhood impacts telomere length and cortisol in preschool children. There was no difference in child telomere length or cortisol between two trial arms of a nutritional supplementation trial that began during pregnancy. The research outcomes indicate lipid-based nutrient supplements, a relatively new form of supplementation, do not have an effect on markers of stress or cellular aging measured in later childhood. PMID: 32063089 [PubMed - as supplied by publisher]
Source: Stress - Category: Research Tags: Stress Source Type: research
Publication date: Available online 19 February 2020Source: Surgery (Oxford)Author(s): Christopher Limb, Timothy RockallAbstractLaparoscopic surgery is currently established as the primary modality for many procedures. In has been associated with a number of benefits over traditional open surgery, including reduced pain, shorter hospital stay and quicker return to work. Despite this, significant operative challenges and the potential for life-threatening complications exist. Surgeons must understand the specialist equipment that is required, along with how to troubleshoot common issues. Furthermore, an appreciation of the d...
Source: Surgery (Oxford) - Category: Surgery Source Type: research
Publication date: Available online 19 February 2020Source: Journal of the American College of RadiologyAuthor(s): Soheil Kooraki, Melina Hosseiny, Lee Myers, Ali GholamrezanezhadAbstractIn December 2019, a novel coronavirus pneumonia was emerged in Wuhan, China. Since then, this highly contagious coronavirus has been spreading worldwide with a rapid rise in the number of death tolls. The novel coronavirus infected pneumonia (NCIP) is characterized by fever, fatigue, dry cough and dyspnea. A variety of chest imaging features have been reported, similar to those found in other types of coronavirus syndromes. The purpose of t...
Source: Journal of the American College of Radiology - Category: Radiology Source Type: research
In conclusion one-piece immediate loading implant is a reliable device for mandible rehabilitation. PMID: 32064846 [PubMed - in process]
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research
Authors: Wang X, Zhang X, He J Abstract On December 31, 2019, the Wuhan Municipal Health Commission announced an outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), China is now at a critical period in the control of the epidemic. The Chinese Government has been taking a series of rapid, comprehensive, and effective prevention and control measures. As the pandemic has developed, a fact has become apparent: there is a serious dearth of emergency medical supplies, and especially an extreme shortage of personal protective equipment such as masks and medical protective clothing. This is one of the...
Source: BioScience Trends - Category: Biomedical Science Tags: Biosci Trends Source Type: research
Introduction Following the initial outbreak of A/H1N1pdm09 in 2009-10, periodic resurgences of the pandemic influenza virus have been reported from India with variable morbidity and mortality. 1, 2 We have earlier reported a recrudescence of A/H1N1pdm09 in 2012-13 in Kashmir region of the northern Indian state of Jammu and Kashmir where influenza is an important cause of acute respiratory infections during the winter months. 3, 4 During the initial months of 2015, an unusual increase in influenza A/H1N1pdm09 activity was observed thoughout India with more than 39000 cases and about 3000 deaths. 5 While the activity was us...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
Conclusion This modelling study shows how the strains of influenza A – "bird flu" – circulating when a person is born give them lifelong protection against new subtypes with the same H protein groups. The researchers call this immune imprinting. This may help to explain the high severity and mortality rate seen among certain groups. For example, the massive flu pandemic of 1918 was an H1N1 strain. This had a very high fatality rate among young adults, which the researchers consider may have been because when they were born (between 1880 and 1900), H3 was the dominant strain. Therefore they had no prot...
Source: NHS News Feed - Category: Consumer Health News Tags: Heart/lungs Medical practice Source Type: news
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