Case Report: Subarachnoid Hemorrhage and Eosinophilic Meningitis due to Disseminated Fascioliasis.
Case Report: Subarachnoid Hemorrhage and Eosinophilic Meningitis due to Disseminated Fascioliasis. Am J Trop Med Hyg. 2020 Jan 13;: Authors: Hughes G, Green CA, Street D, Maurice Y, Henderson J, Woodhouse A, Nicholl D, Scriven JE Abstract Human infection with the trematode Fasciola occurs with a worldwide prevalence of up to 17 million. Sheep and cattle are the normal host. Infection typically results in hepatobiliary disease, but extrahepatic manifestations are occasionally reported. Here, we present the case of a previously healthy 31-year-old Kurdish woman, admitted to hospital with a subarachnoid hemorrhage, eosinophilic meningitis, and lung and liver disease. A diagnosis of Fasciola infection was made based on strongly positive serology in blood and cerebrospinal fluid. The patient improved following treatment with triclabendazole and prednisolone. PMID: 31933459 [PubMed - as supplied by publisher]
We report a case of a fatal Strongyloides stercoralis hyperinfection syndrome (SHS) in a migrant from Kenya, who had been living in Germany for three decades. A short-course oral steroid treatment for Chronic Obstructive Lung Disease (COPD) exacerbation had been administered four weeks prior to the presentation. The initial clinical and radiological findings suggested a mechanical small bowel obstruction as a cause of ileus. Our case highlights the importance of maintaining a high index of suspicion for strongyloidiasis in patients from endemic areas even years after they left the country of origin. It demonstrates that ev...
Authors: Chang JW, Lee HW, Kim BK, Park JY, Kim DY, Ahn SH, Han KH, Kim SU Abstract Background/Aims: The hepatic steatosis index (HSI) is a noninvasive method to assess the severity of hepatic steatosis. Antiviral therapy (AVT) can impact aspartate aminotransferase and alanine aminotransferase levels, which are the main components of the HSI. Thus, we investigated the accuracy of the HSI in detecting hepatic steatosis in patients with chronic hepatitis B (CHB) receiving AVT, compared with those not receiving AVT and in those with nonalcoholic fatty liver disease (NAFLD). Methods: Patients with CHB or NAFLD who unde...
Diagnostic Performance of Serum Asialo α1-Acid Glycoprotein Levels to Predict Liver Cirrhosis. Gut Liver. 2020 Feb 20;: Authors: Lim DH, Kim M, Jun DW, Kwak MJ, Yoon JH, Lee KN, Lee HL, Lee OY, Yoon BC, Choi HS, Kang BK Abstract Background/Aims: To date, studies on various noninvasive techniques have been suggested to evaluate the degree of liver fibrosis. We aimed to investigate the diagnostic performance of serum asialo α1-acid glycoprotein (AsAGP) in the diagnosis of liver cirrhosis compared with chronic hepatitis for clinically useful result. Methods: We conducted a case-control study o...
Conditions: Cystic Fibrosis; Liver Fibroses; Cystic Fibrosis Liver Disease Intervention: Sponsor: Manchester University NHS Foundation Trust Recruiting
Race-based disparities are well documented in the entire spectrum of care for patients with chronic liver disease. The purpose of this study was to determine whether patient race impacts survival following transjugular intrahepatic portosystemic shunt (TIPS) creation for acute variceal bleeding.
Black patients are subject to documented disparities in the entire spectrum of chronic liver disease care, from screening to treatment and transplant organ access. Whether this racial inequity exists in access to endoscopy and/or transjugular intrahepatic portosystemic shunt (TIPS) creation is not known. We analyzed rates of endoscopy and TIPS during admissions for acute variceal bleeding in a national cohort.
Transjugular intrahepatic portosystemic shunt (TIPS) is an interventional radiology procedure to treat complications arising from portal hypertension in patients with liver disease. Postoperative survival following TIPS are dependent on several factors. This purpose of this study is to determine whether machine learning models can accurately predict in-hospital mortality following TIPS and ultimately, be used to develop a computational tool that can stratify patients based on their mortality risk.
Liver biopsy is the gold standard for diagnosing liver disease in patients undergoing evaluation for heart transplant. Obtaining an accurate assessment of the liver is crucial, as it predicts outcomes of heart transplantation. Transabdominal liver biopsy increases the risk of bleeding and can be dangerous due to the limited cardiac reserve of these patients, therefore transvenous approaches are preferable. Studies show that patients with congestive hepatopathy have heterogeneous involvement of the liver.
To assess the safety of performing elective transjugular intrahepatic portosystemic shunt (TIPS) placement for ascites or hepatic hydrothorax in patients with intermediate MELD scores of 11-17 and high MELD scores of 18-24.
Lusutrombopag is an oral, small molecule thrombopoietin receptor agonist approved in Japan and US for treatment of thrombocytopenia (TCP), and in EU for severe TCP, associated with chronic liver disease (CLD) in patients undergoing planned invasive procedures. The degree of TCP may impact treatment response to lusutrombopag and the need for platelet transfusion (PT). This analysis evaluates the increase in platelet count (PC) and maximum PC achieved according to baseline PC.