New Head Injury Data Reinforce Restricted Antipsychotic Use New Head Injury Data Reinforce Restricted Antipsychotic Use

New data on head injury support evidence-based guidance to restrict antipsychotic use in patients with dementia to those with the most severe neuropsychiatric symptoms, and for a short, limited time.Medscape Medical News
Source: Medscape Psychiatry Headlines - Category: Psychiatry Tags: Psychiatry News Source Type: news

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Title: Is Head Injury Causing Dementia? MRI Might ShowCategory: Health NewsCreated: 10/28/2019 12:00:00 AMLast Editorial Review: 10/29/2019 12:00:00 AM
Source: MedicineNet Alzheimer - Category: Geriatrics Source Type: news
ConclusionsMildly elevated tau-PET binding was observed in a subset of amyloid-negative patients at risk for CTE, in a distribution consistent with CTE pathology stages III-IV. FTP-PET may be useful as a biomarker of tau pathology in CTE but is unlikely to be sensitive to early disease stages.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Early treatment with tranexamic acid could save many lives Related items fromOnMedica Risk/benefit balance of alteplase shifts quickly Earlier thrombolysis improves stroke outcomes Alteplase use linked to reduction in disability after stroke Lengthen GP training to include dementia New guidance to prevent strokes
Source: OnMedica Latest News - Category: UK Health Source Type: news
Hernia patients had a higher incidence rate and hazard ratio of dementia than those in non ‐hernia group. Advanced age, hypertension, head injury, and stroke were found to be risk factors for dementia. Patients with high socioeconomic status and history of coronary artery disease were unlikely to develop dementia in our cohort study. AbstractObjectiveMatrix metalloproteinases (MMPs) may play a role in the pathophysiology of neurodegenerative disease and hernia formation. This retrospective cohort study was designed to assess whether there is an association between hernia and the risk of dementia.Materials and MethodsPati...
Source: Brain and Behavior - Category: Neurology Authors: Tags: ORIGINAL RESEARCH Source Type: research
This article highlights some of these challenges in the design of lifestyle studies in PD, and suggests a more coordinated international effort is required, including ongoing longitudinal observational studies. In combination with pharmaceutical treatments, healthy lifestyle behaviors may slow the progression of PD, empower patients, and reduce disease burden. For optimal care of people with PD, it is important to close this gap in current knowledge and discover whether such associations exist. Introduction Parkinson's disease (PD) is an age-related complex progressive neurodegenerative disorder, with key p...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Beta Amyloid Deposition Is Not Associated With Cognitive Impairment in Parkinson's Disease Tracy R. Melzer1,2,3†, Megan R. Stark1,2†, Ross J. Keenan1,4, Daniel J. Myall1, Michael R. MacAskill1,2, Toni L. Pitcher1,2,3, Leslie Livingston1,2, Sophie Grenfell1, Kyla-Louise Horne1,2, Bob N. Young1, Maddie J. Pascoe1, Mustafa M. Almuqbel1,2,4, Jian Wang5, Steven H. Marsh6, David H. Miller1,2,7, John C. Dalrymple-Alford1,2,3,8 and Tim J. Anderson1,2,3,9* 1New Zealand Brain Research Institute, Christchurch, New Zealand 2Department of Medicine, University of Otago, Christchurch, New Zealand 3Brain Rese...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
In this study, we assessed the relationship of ΔHR (difference between resting HR and HRt) and recovery from SRC. Using a retrospective cohort design, we compared acutely (30 days) in RG (p = 0.01) and PG (p = 0.04). A ΔHR of ≤50 bpm on the BCTT is 73% sensitive and 78% specific for predicting prolonged recovery in concussed adolescents who were prescribed the current standard of care (i.e., cognitive and physical rest). Introduction Sport-related concussion (SRC), a type of mild traumatic brain injury (mTBI), is a significant public health concern (1, 2). Concussion is defined as reversible neurolog...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusion: Financial compensation was related to victims' long-term severity of impairment, although some extreme cases with severe disability were granted very poor compensation. Introduction Traumatic brain injury (TBI) occurs at a high incidence with more than 50 million people sustaining a TBI each year worldwide (1). Related to this, people with TBI are frequently involved in a litigation with claim compensation proceedings because another person was partly or wholly at fault for causing the injury, in particular in the context of road traffic accidents. While lawsuits after TBI are frequent, research...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
This study aimed to evaluate the impact of self-construal on neurocognitive functions in older adults. A total of 86 community-dwelling older adults 60 years and older were assessed with three common self-report measures of self-construal along individualism and collectivism (IC). A cognitive battery was administered to assess verbal and non-verbal fluency abilities. Latent profile analysis (LPA) was used to categorize individuals according to IC, and one-way analyses of covariance (ANCOVA), including relevant covariates (e.g., ethnicity, gender, linguistic abilities), were used to compare neurocognitive functions between ...
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
MRC Laboratory of Molecular Biology researchers reveal atomic structures of the abnormal tau filaments associated with chronic traumatic encephalopathy, a head injury-associated neurodegenerative disease, differ in structure from those seen in Alzheimer’s disease.
Source: Medical Research Council General News - Category: Research Source Type: news
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