Longitudinal assessment of the platelet transcriptome in advanced heart failure patients following mechanical unloading.

In conclusion, advanced HF is associated with marked alterations in the platelet transcriptome. While LVAD implantation to off load the failing heart results in resolution in the majority of differentially expressed genes, a subset of the platelet transcriptome remains persistently altered. PMID: 31934818 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31934818?dopt=Abstract

Source: Platelets - January 16, 2020 Category: Hematology Tags: Platelets Source Type: research